Results 61 to 70 of about 1,558,961 (274)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
(De)constructing health news: an analysis of the lifecycle of elderly-related news stories through multi-sited, linguistic ethnographic research [PDF]
, 2014 ‘(De)constructing Health News’ is a transdisciplinary project of the Health, Media & Society research centre (Ghent University), aiming at investigating the processes and stakeholder interaction involved in the (de)construction of elderly-related health ...
Declercq, Jana
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Diversity disorders: Ethnicity and newsroom cultures [PDF]
Conflict & Communication Online, 2009 Sweden, as many other European countries, has been engaged in the debate concerning the relationships between social cohesion and the media. The article examines the tension between officially expressed attitudes and diversity goals of Swedish newsrooms ...
Gunilla Hultén
doaj
Production of Dry Table Wines Zooming Article [PDF]
, 2015 Paul Bjelland of Bjelland Vineyards pens this article published in Roseburg\u27s News-Review. Umpqua Valley, including Bjelland Vineyards, foresees a large expansion of dry table wine production from Cabernet Sauvignon to Pinot-Chardonnay. The article is
Bjelland, Paul
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Detecting Textual Reuse in News Stories, At Scale
International Journal of Communication, 2019 Motivated by the debate around “churnalism” and online media, this article develops, evaluates, and validates a computational method for detecting shared text between different news articles, at scale, using n-gram shingling.
Tom Nicholls
doaj +2 more sources
Possible Russian development paths and their implications for Europe: some back-of-the-envelope musings [PDF]
, 2006 This chapter examines the potential implications for the European Union and for EU-Russian relations of recent developments in Russian economic policy. Its principal argument may be stated simply.
Tompson, William
core