Results 71 to 80 of about 45,768 (259)
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu +20 more
wiley +1 more source
All News Is Not the Same: Divergent Effects of News Platforms on Civic and Political Participation
Online news platforms are often grouped together as “online news” or “social media,” yet each delivers news in a distinctive way. This article examines different online news platforms—including legacy news organization website and news apps, instant ...
Nuri Kim +3 more
doaj
REVIEW: Cyberspace, kavabowls and hot news in the Pacific
Review of Tahiti Pacifique, Tahiti Beach Press, The National, Post-Courier, Samoa Observer, Tonga Chronicle, Matangi Tonga, Uni Tavur, Papua Niugina Nius, Online Journalist's 'Tonga Page', CocoNet Wireless, Pacific Islands Internet services, Cafe Pacific,
David Robie
doaj +1 more source
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo +14 more
wiley +1 more source
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
SPADE integrates spatial transcriptomics with single‐cell RNA sequencing by using cell–cell communications (CCC) as a guide for spatial mapping. It improves cell‐type localization, enhances sparse gene‐expression signals, and reveals CCC programs at single‐spot resolution.
Xinyi Li, Ning Zhang, Zijie Jin
wiley +1 more source
An exciting Approach to Theoretical Spectroscopy
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno +29 more
wiley +1 more source
In this article, we investigate how news selection on news websites is influenced by popularity indicators and news factor intensities. For Internet users, popularity indicators such as comment counts, published in the context of news items, might ...
Ines Engelmann, Manuel Wendelin
doaj
A Selection of News from the Institute
Details of news and events can be found throughout the year on the Institute’s website at http://www.ucl.ac.uk/archaeology/calendar.
doaj +2 more sources
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang +10 more
wiley +1 more source

