Results 101 to 110 of about 1,464,578 (290)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Levi Pennington Writing to Missionaries, October 8, 1946
, 1946 Levi Pennington writing the missionary letter to missionaries on the field and providing news on the proposal of the missionary board to purchase a Bolivian farm for use as a missionary house and the Friends work in the local drive for overseas relief.
Pennington, Levi T.
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
THE MAIN PRINCIPLES AND TECHNIQUES OF RADIO NEWS WRITING [PDF]
Social Sciences and Education Research Review, 2018 Radio broadcast journalism has certain principles and techniques which are always to be taken into consideration when writing a script. News writing for radio is based on some rigors meant to assure that the public will receive the information properly ...
Davian VLAD
doaj
Annotating a corpus of Early Modern English writing for categories of discourse presentation [PDF]
, 2012 This article discusses the process of annotating a small corpus of Early Modern English writing that we have constructed in order to investigate the diachronic development of speech, writing and thought presentation.
McIntyre, Dan, Walker, Brian
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
KomunikatorThe emergence of Artificial Intelligence (AI) technology in journalism has brought about significant changes. Equipped with AI-powered tools, this technology has become an integral part of journalistic work, transforming the way news is processed.
Indah Kurnianti +3 more
doaj +1 more source
Peningkatan Keterampilan Menulis Berita Dengan Pendekatan Terpadu Dan Media Gambar Pada Siswa Kelas VIII SMP Negeri 1 Teras [PDF]
, 2015 The purpose of the research is to increase news-writing skills by applying integrated approach and images utilization.The research is a type of action research which was conducted in 3 cycles.
Hartati, S. (Sri)
core