Results 101 to 110 of about 17,094,571 (296)

NEW CONJUGATE GRADIENT METHOD FOR ACCELERATED CONVERGENCE AND COMPUTATIONAL EFFICIENCY IN UNCONSTRAINED OPTIMIZATION PROBLEMS

open access: yesBarekeng
Conjugate gradient (CG) algorithms play an important role in solving large-scale unconstrained optimization problems due to their low memory requirements and strong convergence properties.
Basim A. Hassan   +3 more
doaj   +1 more source

A numerical method for a stefan-type problem

open access: yesMathematical Modelling and Analysis, 2011
A Stefan-type problem is considered. This is an initial-boundary value problem on a composite domain for a parabolic reaction-diffusion equation with a moving interface boundary.
G. Shishkin, L. Shishkina, K. Cronin
doaj   +1 more source

Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model

open access: yesAdvanced Science, EarlyView.
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li   +8 more
wiley   +1 more source

A Subspace Preconditioned LSQR Gauss-Newton Method with a Constrained Line Search Path Applied to 3D Biomedical Microwave Imaging

open access: yesInternational Journal of Antennas and Propagation, 2015
Three contributions that can improve the performance of a Newton-type iterative quantitative microwave imaging algorithm in a biomedical context are proposed. (i) To speed up the iterative forward problem solution, we extrapolate the initial guess of the
Jürgen De Zaeytijd, Ann Franchois
doaj   +1 more source

The Shadow of the Soul Breaker: Solitary Confinement, Cocaine, and the Disintegration of Huey P. Newton [PDF]

open access: yes, 2015
The article probes the impact of prison on Huey P. Newton, founder of the Black Panther Party. Incarcerated for three years in various locations in California, Newton descended into cocaine addiction and criminality soon after his 1970 release.
Street, Joe
core   +1 more source

Near‐Infrared Fluorescent PROTAC Enables Theranostic Imaging and Selective Tau Degradation in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Here, we report a novel NIR fluorescent PROTAC platform that enables real‐time imaging and targeted degradation of Alzheimer's p‐Tau. Our lead compound effectively clears p‐Tau, reduces APP/Aβ, and alleviates cognitive deficits in AD mice. This work demonstrates a theranostic strategy for visualizing degradation and developing next‐generation AD ...
Ziwei Ren   +11 more
wiley   +1 more source

Ground-Penetrating Radar Dual-Parameter Waveform Inversion Based on Limited-Memory Truncated Newton Method

open access: yesApplied Sciences
In penetrating radar waveform inversion, the Limited-memory Broyden–Fletcher–Goldfarb–Shanno (L-BFGS) algorithm only needs to store the most recent gradients and model parameters to approximate the Hessian matrix, which effectively keeps computational ...
Xintong Liu   +4 more
doaj   +1 more source

A New Three–Term Conjugate Gradient Method with Descent Direction for Unconstrained Optimization

open access: yesMathematical Modelling and Analysis, 2016
In this paper, we propose a three–term PRP–type conjugate gradient method which always satisfies the sufficient descent condition independently of line searches employed.
XiaoLiang Dong   +4 more
doaj   +1 more source

Wilberforce Newton

open access: yes, 2018
This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete.
Stephen Family, Newton Family
core  

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy