Results 131 to 140 of about 2,811,364 (363)

A Rural Next Generation Network (R-NGN) and Its Testbed

Journal of ICT Research and Applications, 2013
Rural Next Generation Networks (R-NGN) technology allows Internet protocol (IP) based systems to be used in rural areas. This paper reports a testbed of R-NGN that uses low cost Ethernet radio links, combined with media gateways and a softswitch.
Armein Z. R. Langi
doaj  

Regulation of NGN: Structural Separation, Access Regulation, or No Regulation at All? [PDF]

Since the introduction of Next Generation Networks (NGNs) by telecommunication network operators, national regulators have begun to adapt their access regulation regimes to the new technological conditions.
Hirschhausen, Christian von, Kirsch, Fabian   +1 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

QoS Guarantee for Next Generation Network in the VoIP System

Dianxin kexue, 2014
For the QoS of VoIP system, integrating the service based mechanism of network policy control within 3GPP IMS into QoS of VoIP, the SIP was adopted as signaling protocol.
Hongjiao Peng, Shangdong Liu, Xiamei Chen   +2 more
doaj   +2 more sources

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

New network sharing technologies for next generation network evolution

Dianxin kexue
Indirect network sharing is considered as an innovative network sharing method, which has a broad application prospect and important social value, when achieves the problems in 5G-Advanced (5G-A) network sharing development and promotes the further ...
WEI Qun, WANG Zelin, LONG Qingliang, GAO Gongying, XING Tianqi, CHENG Cuiru   +5 more
doaj  

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

End-to-end multipath transport layer architecture oriented the next generation network

Tongxin xuebao, 2010
To solve the problem of inefficient transmission using multiple interfaces of multihome terminal in the tradition network,an end-to-end multipath transport layer architecture—E2EMP oriented the next generation network was presented.Through distributing ...
XUE Miao, GAO De-yun, ZHANG Si-dong, ZHANG Hong-ke   +3 more
doaj   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source