Results 211 to 220 of about 1,444,385 (351)

Performance assessment of DNA sequencing platforms in the ABRF Next-Generation Sequencing Study

Nature Biotechnology, 2021
J. Foox, S. Tighe, C. Nicolet, J. Zook, M. Byrska-Bishop, Wayne E. Clarke, Michael M. Khayat, M. Mahmoud, Phoebe K Laaguiby, Zachary T. Herbert, Derek Warner, G. Grills, J. Jen, S. Levy, Jenny Z. Xiang, A. Alonso, Xia Zhao, Wenwei Zhang, Fei Teng, Yonggang Zhao, Haorong Lu, G. Schroth, G. Narzisi, W. Farmerie, F. Sedlazeck, D. Baldwin, C. Mason   +26 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Monitoring Variant Allele Fraction in VEXAS Syndrome: A Comparison of Digital PCR and Next-Generation Sequencing. [PDF]

EJHaem
Exposito-Bey A, Montes-Cano MA, Payán-Pernía S, García-Lozano JR, González-Escribano MF.   +4 more
europepmc   +1 more source

Focused Size Selection of Cell-Free DNA Samples for Liquid Biopsy Applications that Rely on Next-Generation Sequencing

, 2019
Christopher K. Raymond
openalex   +1 more source

Error filtering, pair assembly and error correction for next-generation sequencing reads

Bioinform., 2015
Robert C. Edgar, H. Flyvbjerg
semanticscholar   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

The utility of next-generation sequencing in metastatic prostate cancer FNA biopsies. [PDF]

Cancer Cytopathol
Sirohi D, Cornelia Ding CK, Stohr BA, Balassanian R, Vohra P, Aggarwal R, Chan E, Greenland NY.   +7 more
europepmc   +1 more source

Detection of chromosomal abnormalities in spontaneous miscarriage by low‑coverage next‑generation sequencing

, 2020
Fenxia Li, Mei‐Juan Xie, Shoufang Qu, Dan He, Long Yang Wu, Zhikun Liang, Yingsong Wu, Fang Yang, Xuexi Yang   +8 more
openalex   +2 more sources

Compression of Next-Generation Sequencing Data and of DNA Digital Files [PDF]

, 2020
Bruno Carpentieri
openalex   +1 more source

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source