In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Durable remission despite transplantation with active disease in therapy-related NUP98::TOP1-rearranged acute myeloid leukemia. [PDF]
Cimino G +18 more
europepmc +1 more source
Sex-Specific Patterns of Taste Dysfunction, Their Relationships with α-Synuclein Profiling, and Supervised Learning-Based Diagnosis in Parkinson's Disease (PD). [PDF]
Melis M +11 more
europepmc +1 more source
Cerium-Doped ZnO Thin Films for Photocatalysts. [PDF]
Bancheva-Koleva P +6 more
europepmc +1 more source
Krill Oil Supplementation and Muscle Health in Older Age: Broad Benefits Without Boundaries? [PDF]
Calvani R, Marzetti E, Picca A.
europepmc +1 more source
Design of active interlayer space in layered oxysulfide photocatalysts NaMTiO<sub>2.2</sub>S<sub>1.8</sub> (M = lanthanoid) for efficient visible light hydrogen evolution. [PDF]
Ishii Y +8 more
europepmc +1 more source
Complete genome sequence of <i>Cronobacter muytjensii</i> bacteriophage vB_Cmu_VP5. [PDF]
Durovka P +3 more
europepmc +1 more source

