Results 191 to 200 of about 523,633 (260)

The diagnostic and prognostic utility of blood metagenomic next-generation sequencing for invasive pulmonary aspergillosis. [PDF]

Microbiol Spectr
Chen Y, Tang X, Lu S, Guo L, Wang L, Min L, Niu T, Zhou Y.   +7 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Comparative Profiling of Yeast Communities in Kefir Grains and Liquid Kefir Using ITS Amplicon Next-Generation Sequencing. [PDF]

Int J Food Sci
Kurniawan, Milanda T, Kusuma SAF.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

The role of targeted next-generation sequencing and ultrasound in diagnosing fetal cytomegalovirus infection: a case report. [PDF]

Front Pediatr
Sun J, Gao W, Tan H.
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Targeted next-generation sequencing confirms rabies in a patient with unknown exposure: a case report. [PDF]

Front Med (Lausanne)
Li R, Jin C, Zhang Z, Zhang C, Chen X.
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Trends and Disparities in the Use of Next-Generation Sequencing in Patients With Cancer in the United States.

JAMA Netw Open
Hage Chehade C, Ozay ZI, Jo Y, Gebrael G, Sayegh N, Ostrowski M, Srivastava A, Garg D, Hardy T, Murdock EG, Narang A, Mathew Thomas V, Li H, Maughan BL, Roy S, Agarwal N, Swami U.   +16 more
europepmc   +1 more source