Results 41 to 50 of about 28,077 (280)

Mineralogical and petrographic characterization of the Cerrillo Blanco Iberian sculptures [PDF]

open access: yes, 2023
This research was funded by the following projects: (ECODIGICOLOR), grant number TED2021‑132023B‑I00, supported MCIN/AEI /http://dx.doi.org/10.13039/501100011033 and Unión Europea NextGenerationEU/ PRTR (Proyectos estratégicos orientados a la transición ...
Doménech‑Carbó, Teresa   +4 more
core   +1 more source

Reformas jurídicas estatales para la gestión de los fondos NGEU: análisis y reflexión desde el derecho administrativo

open access: yesRevista Catalana de Dret Públic, 2021
En la UE, la crisis económica generada por la pandemia ha requerido la puesta en marcha de un esfuerzo financiero extraordinario: los fondos europeos NextGenerationEU.
María Amparo Salvador Armendáriz
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

El futuro de la industria española

open access: yesRevista de Economía Mundial, 2021
Este artículo define una estrategia de desarrollo industrial para España que debe permitir, no sólo superar el importante daño originado por las dos recientes crisis – la Gran Recesión y la pandemia provocada por el coronavirus – sino también aumentar ...
Rafael Myro
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The impact of the COVID-19 on policies and investments of the European Green Deal.

open access: yesEuropean Journal of Volunteering and Community-Based Projects, 2021
The paradigm generated on world systems and models by COVID-19 has led to the search for new solutions. The European Commission has generated and strengthened the previously defined sustainability and Green Deal policies. The NextGenerationEU fund could
Paolo Biancone   +2 more
doaj   +2 more sources

Quantitative MRI Uncovers Subtle Cortical Damage in Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera   +20 more
wiley   +1 more source

EU Policies and Goals of the Green Transition of Bulgaria and Romania for 2030 [PDF]

open access: yesGlobal Economic Observer, 2023
The article analyses the policies of the EU Green Deal, focusing on the initiatives NextGenerationEU, Fit for 55 Package, Just Transition Mechanism, and RePowerEU Plan under the EU program period 2021-2027.
IANA PALIOVA
doaj  

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