Results 41 to 50 of about 38,263 (282)

Inspiration for a next generation EU [PDF]

open access: yes
What do you want the future to look like? In which future would you like to live? These are questions of high relevance for policy were at the heart of the Conference on the Future of Europe that ended in May 2022.
BOL Erica, BONTOUX Laurent
core   +1 more source

Nanoscale zero-valent iron mitigates arsenic mobilization and accumulation in Sinapis alba grown on a metal(loid)-polluted soil treated with a dunite mining waste-compost amendment [PDF]

open access: yes, 2023
NANOCAREM project (AEI/Spain, FEDER/EU) [MCI-20-PID2019-106939GB-I00]; a Severo Ochoa grant [Ref. BP20-192]; the European Union-NextGenerationEU, Ministerio de Universidades, and Plan de Recuperación, Transformación y Resiliencia, postdoctoral grant ...
Baragaño Coto, Diego   +5 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Heuristic absorption calculation in bilayered media from a white Monte Carlo dataset [PDF]

open access: yes
Monte Carlo (MC) simulations can adequately describe photon migration in layered media; however, storing and querying the resulting dataset may be computationally prohibitive when detailed path data are needed for each photon trajectory.
Martelli, Fabrizio
core   +4 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

El futuro de la industria española

open access: yesRevista de Economía Mundial, 2021
Este artículo define una estrategia de desarrollo industrial para España que debe permitir, no sólo superar el importante daño originado por las dos recientes crisis – la Gran Recesión y la pandemia provocada por el coronavirus – sino también aumentar ...
Rafael Myro
doaj   +1 more source

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Reformas jurídicas estatales para la gestión de los fondos NGEU: análisis y reflexión desde el derecho administrativo

open access: yesRevista Catalana de Dret Públic, 2021
En la UE, la crisis económica generada por la pandemia ha requerido la puesta en marcha de un esfuerzo financiero extraordinario: los fondos europeos NextGenerationEU.
María Amparo Salvador Armendáriz
doaj   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

open access: yesAdvanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi   +3 more
wiley   +1 more source

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