Results 191 to 200 of about 290,563 (288)
The NAVIGATE Registry: Early Endovascular Repair of the Ascending Aorta With the Nexus Ascending Module. [PDF]
Mosquera VX +6 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
From Alliance to Nexus: Rethinking Digital Therapeutic Relationships. [PDF]
B Cadena D, Walther JU, Brünahl CA.
europepmc +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Correction to: Functional anisotropy of the elephant trunk skin: A biological blueprint for grasping, protection, and tactile sensing. [PDF]
europepmc +1 more source
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Correction to: Nudging recommendation algorithms increases news consumption and diversity on YouTube. [PDF]
europepmc +1 more source
Liver sinusoidal endothelial cell fenestrations in metabolic liver disease: from molecular mechanisms to therapeutic perspectives. [PDF]
Al-Mughalles AS +10 more
europepmc +1 more source

