Results 141 to 150 of about 67,096 (237)

Eye disorders in neurofibromatosis (NF1).

open access: yesCollegium antropologicum, 2005
Neurofibromatosis type 1 (NF 1) is an autosomal dominant disorder with high index of spontaneous mutations and extremely varied and impredictible clinical manifestations. The aim of this work was to give an account of eye disorders in NF1. 132 patients of age 0-16 years with NF1 were followed up for 15 years.
Kordić, Rajko   +4 more
openaire   +3 more sources

Case Report: Parapharyngeal Leiomyosarcoma Mimicking Neurofibroma

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
Neurofibroma and leiomyosarcomas are rare tumors of the head and neck with similar imaging characteristics of T2 hyperintensity on MRI that can present with neurological deficits. However, leiomyosarcomas are malignant, and early diagnosis is critical to improved survival. Immunohistochemistry is crucial for assigning line of differentiation in spindle
Carson Brantley   +3 more
wiley   +1 more source

Pathology in Practice [PDF]

open access: yes, 2017
Lofts, R   +3 more
core   +1 more source

Non‐Functional Paraganglioma of the Urinary Bladder: A Rare Cause of Bladder Tumor

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction Paragangliomas of the urinary bladder (PUBs) are rare neuroendocrine tumors, representing less than 0.06% of all bladder neoplasms. While most are functional and associated with catecholamine excess, approximately 15% are non‐functional, often presenting asymptomatically and discovered incidentally.
Matt Wainstein   +4 more
wiley   +1 more source

Chromatin Accessibility in Cancer: Biological Functions, Mechanisms, Therapeutic Potential, and Future Directions

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Cancer remains the leading cause of mortality worldwide, and drug resistance further underscores the urgent need for innovative therapeutic strategies. Chromatin, a stable yet highly dynamic nucleoprotein complex, serves as the primary carrier of genetic material in eukaryotic cells.
Wentao Xia   +4 more
wiley   +1 more source

Single Nucleotide Polymorphism Microarray Analysis Unveils Copy‐Number Abnormalities and Genetic Heterogeneity in Malaysian Childhood B‐Cell Precursor Acute Lymphoblastic Leukemia

open access: yesMolecular Genetics &Genomic Medicine, Volume 14, Issue 3, March 2026.
B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL) is a prevalent pediatric hematologic malignancy characterized by diverse chromosomal aberrations that significantly influence its prognosis. This study aimed to comprehensively characterize the genomic landscape of childhood BCP‐ALL in a cohort of 55 Malaysian patients.
Nor Soleha Mohd Dali   +12 more
wiley   +1 more source

Multifacet Roles of Cellular Senescence in Cancer: Mechanisms and Therapeutic Implications

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Cellular senescence shapes tumor progression through both antitumor and protumor mechanisms. Senescence triggered by telomere shortening restricts malignant transformation and limits tumor cell proliferation, while the senescence‐associated secretory phenotype (SASP) secretion enhances antitumor immunity by activating cytotoxic T cells.
Huajie Mao   +5 more
wiley   +1 more source

Treating Severe Cervical Deformity in Neurofibromatosis 1 with a Posterior Fibula Graft from Occiput to Thoracic Spine: A Case Report

open access: yesSpine Surgery and Related Research
Bungo Otsuki   +4 more
doaj   +1 more source

Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing

open access: yesCancer Science, Volume 117, Issue 3, Page 797-806, March 2026.
Our findings indicate that a pediatric/AYA‐specific targeted panel deployed in a hospital can deliver rapid, clinically actionable molecular insights with high diagnostic and prognostic yield. This complements larger sequencing platforms by offering speed, focused content, and easier interpretation.
Masato Kojima   +8 more
wiley   +1 more source

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