The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease [PDF]
Acknowledgements: Authors want to express their gratitude to Dr. P. Davies (Albert Einstein College of Medicine, Bronx, NY, USA) and Lester I. Binder (NorthWestern, Chicago, IL, USA) for the generous gift of mAbs (TG-3, Alz-50, and MC1), and (TauC-3 ...
Cárdenas-Aguayo, María C +10 more
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Nuclear tau and its potential role in Alzheimer’s disease [PDF]
Tau protein, found in both neuronal and non-neuronal cells, forms aggregates in neurons that constitutes one of the hallmarks of Alzheimer’s disease (AD).
Al-Hilaly, Youssra +2 more
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Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]
The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
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To investigate the peach fruit flesh types (soft-melting, hard-melting, stonyhard and non-melting) and harvest maturity level suitable for near-freezing temperature storage (NFTS), eight peach cultivars that had four flesh types were used as test ...
Binbin Zhang +6 more
doaj +1 more source
Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects [PDF]
Many neurodegenerative diseases exhibit axonal pathology, transport defects, and aberrant phosphorylation and aggregation of the microtubule binding protein tau. While mutant tau protein in frontotemporal dementia and parkinsonism linked to chromosome 17
Falzone, Tomas Luis +6 more
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Do NFTs Sound Good? An Exploratory Study on Audio NFTs and Possible Avenues
Crypto, non-fungible tokens (NFTs), and the metaverse have taken a massive place in our daily conversations and are highly valued. Moreover, NFTs range from luxury fashion to art, and sound is no exception, although it still needs to be explored.
Clara E. Fernandes, Ricardo Morais
doaj +1 more source
The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease [PDF]
A significant amount of evidence suggests that the p38-mitogen-activated protein kinase (MAPK) signalling cascade plays a crucial role in synaptic plasticity and in neurodegenerative diseases.
Corrêa, Sônia A. L. +1 more
core +3 more sources
Rethinking Property Rights, Relations, and Wealth Inequality in the Age of Non-Fungible Tokens
Blockchain technology and the possibility of its impacts entered the world with the printing of the first Bitcoin block in 2009. Although overshadowed by Bitcoin due to its popularity, blockchain has a potential far beyond Bitcoin.
Umut Yertüm
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Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo. [PDF]
Amyloid imaging represents a major advance in neuroscience, enabling the detection and quantification of pathologic protein aggregations in the brain. In this review we survey current amyloid imaging techniques, focusing on positron emission tomography ...
Jagust, WJ, Rabinovici, GD
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One of the pressing issues in the modern world is the problem of trust in authority. Cultural heritage and the challenges associated with its acknowledgment and preservation often directly influence political processes both within countries and in ...
Denis A. Gromyko
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