Results 61 to 70 of about 43,575 (292)

Alterations of clock gene RNA expression in brain Regions of a triple transgenic model of Alzheimer's Disease [PDF]

open access: yes, 2017
A disruption to circadian rhythmicity and the sleep/wake cycle constitutes a major feature of Alzheimer's disease (AD). The maintenance of circadian rhythmicity is regulated by endogenous clock genes and a number of external Zeitgebers, including light ...
@corresponding, Author   +14 more
core   +1 more source

The use of blockchain technology for preserving cultural heritage and its impact on political processes

open access: yesRUDN Journal of Public Administration
One of the pressing issues in the modern world is the problem of trust in authority. Cultural heritage and the challenges associated with its acknowledgment and preservation often directly influence political processes both within countries and in ...
Denis A. Gromyko
doaj   +1 more source

Rethinking Property Rights, Relations, and Wealth Inequality in the Age of Non-Fungible Tokens

open access: yesİstanbul İktisat Dergisi, 2023
Blockchain technology and the possibility of its impacts entered the world with the printing of the first Bitcoin block in 2009. Although overshadowed by Bitcoin due to its popularity, blockchain has a potential far beyond Bitcoin.
Umut Yertüm
doaj   +1 more source

Axonal stress kinase activation and tau misbehavior induced by kinesin-1 transport defects [PDF]

open access: yes, 2009
Many neurodegenerative diseases exhibit axonal pathology, transport defects, and aberrant phosphorylation and aggregation of the microtubule binding protein tau. While mutant tau protein in frontotemporal dementia and parkinsonism linked to chromosome 17
Falzone, Tomas Luis   +6 more
core   +1 more source

Calcium in the initiation, progression and as an effector of Alzheimer's disease pathology. [PDF]

open access: yes, 2009
The cause(s) of sporadic Alzheimer's disease (sAD) are complex and currently poorly understood. They likely result from a combination of genetic, environmental, proteomic and lipidomic factors that crucially occur only in the aged brain.
Green, Kim N
core   +1 more source

NFTs for Open-Source and Commercial Software Licensing and Royalties

open access: yesIEEE Access, 2023
Software licenses are legal agreements of sale and usage among software developers and clients. Such legal agreements are crucial to effectively manage ownership and protect the rights of involved parties. Today’s software licensing mechanisms are mostly
M. Madine   +3 more
semanticscholar   +1 more source

The role of p38 MAPK and its substrates in neuronal plasticity and neurodegenerative disease [PDF]

open access: yes, 2012
A significant amount of evidence suggests that the p38-mitogen-activated protein kinase (MAPK) signalling cascade plays a crucial role in synaptic plasticity and in neurodegenerative diseases.
Corrêa, Sônia A. L.   +1 more
core   +3 more sources

EXPLORANDO EL LABERINTO FISCAL DE LOS ACTIVOS DIGITALES: EL CASO DE LOS NFTS

open access: yesCrónica Tributaria
Los tokens no fungibles, o NFTs, son activos digitales únicos e indivisibles que han ganado popularidad en el mercado del arte, los videojuegos y la música.
Estefanía Harana Suano
doaj   +3 more sources

Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo. [PDF]

open access: yes, 2009
Amyloid imaging represents a major advance in neuroscience, enabling the detection and quantification of pathologic protein aggregations in the brain. In this review we survey current amyloid imaging techniques, focusing on positron emission tomography ...
Jagust, WJ, Rabinovici, GD
core   +2 more sources

Gathering for Free: Embedding Economic Incentives in Social Networks Shape the Diffusion of NFTs

open access: yesJournal of Social Computing
The digital innovation accompanied by explicit economic incentives have fundamentally changed the process of innovation diffusion. As a representative of digital innovation, NFTs (Non-Fungible Tokens) potentially offer new revenue streams in the digital ...
Zhe LI, Tianfang ZHAO, Hongjun ZHU
doaj   +1 more source

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