Results 121 to 130 of about 11,425 (225)

Application of phage display to high throughput antibody generation and characterization. [PDF]

, 2007
We have created a high quality phage display library containing over 1010 human antibodies and describe its use in the generation of antibodies on an unprecedented scale.
Buckell, J., Buckell, J., Chapple, S.D.J., Chapple, S.D.J., Clarke, K.F., Clarke, K.F., Clementel, V., Clementel, V., Conquer, J.S., Conquer, J.S., Crofts, A.M., Crofts, A.M., Crowther, S.R.E., Crowther, S.R.E., Dyson, M.R., Dyson, M.R., Flack, G., Flack, G., Griffin, G.J., Griffin, G.J., Hooks, Y., Hooks, Y., Howat, W.J., Howat, W.J., Kolb-Kokocinski, A., Kolb-Kokocinski, A., Kunze, S., Kunze, S., Martin, C.D., Martin, C.D., Maslen, G.L., Maslen, G.L., McCafferty, J., McCafferty, J., Mitchell, J.N., Mitchell, J.N., O'Sullivan, M., O'Sullivan, M., Perera, R.L., Perera, R.L., Pope, A.R., Pope, A.R., Roake, W., Roake, W., Schofield, D.J., Schofield, D.J., Shadbolt, S.P., Shadbolt, S.P., Vincent, K.J., Vincent, K.J., Warford, A., Warford, A., Wilson, W.E., Wilson, W.E., Xie, J., Xie, J., Young, J.L., Young, J.L.   +57 more
core   +2 more sources

The statistical mechanics of complex signaling networks : nerve growth factor signaling

, 2004
It is becoming increasingly appreciated that the signal transduction systems used by eukaryotic cells to achieve a variety of essential responses represent highly complex networks rather than simple linear pathways. While significant effort is being made
Arkin A, Brown K S, Brown K S Sethna J P, Chen K C, Fletcher R, Goldbeter A, Greene L A, Hastings W K, Kirkpatrick S, Laub M T, Marquardt D W, Metropolis N, Newman M E J, Press W H, Robert C P, Stryer L, Traverse S   +16 more
core   +1 more source

Novel method for the isolation of adipose stem cells (ASCs) [PDF]

, 2009
Adipose stem cells (ASCs) represent a cell population with great potential for tissue engineering applications. Several articles have been published showing the proliferation and differentiation potential, the markers and the wide range of potential ...
Castro-Malaspina, Fraser, Goh, Marin, Quarto, Rodbell, Rodbell, Rodbell, Solchaga, Tholpady, Van, Van   +11 more
core   +1 more source

ABCA7-dependent induction of neuropeptide Y is required for synaptic resilience in Alzheimer’s disease through BDNF/NGFR signaling

Cell Genomics
Summary: Genetic variants in ABCA7, an Alzheimer’s disease (AD)-associated gene, elevate AD risk, yet its functional relevance to the etiology is unclear. We generated a CRISPR-Cas9-mediated abca7 knockout zebrafish to explore ABCA7’s role in AD.
Hüseyin Tayran, Elanur Yilmaz, Prabesh Bhattarai, Yuhao Min, Xue Wang, Yiyi Ma, Ni Wang, Inyoung Jeong, Nastasia Nelson, Nada Kassara, Mehmet Ilyas Cosacak, Ruya Merve Dogru, Dolly Reyes-Dumeyer, Jakob Mørkved Stenersen, Joseph S. Reddy, Min Qiao, Delaney Flaherty, Tamil Iniyan Gunasekaran, Zikun Yang, Nathalie Jurisch-Yaksi, Andrew F. Teich, Takahisa Kanekiyo, Giuseppe Tosto, Badri N. Vardarajan, Özkan İş, Nilüfer Ertekin-Taner, Richard Mayeux, Caghan Kizil   +27 more
doaj   +1 more source

Data from Epigenetic Inactivation and Tumor-Suppressor Behavior of NGFR in Human Colorectal Cancer

, 2023
Zuli Yang, Hao Chen, Li‐Jun Huo, Zihuan Yang, Yang Bai, Xinjuan Fan, Beibei Ni, Lekun Fang, Jun Hu, Junsheng Peng, Lei Wang, Jian‐Ping Wang   +11 more
openalex   +1 more source

Resveratrol Induces Autophagy and Apoptosis in Non-Small-Cell Lung Cancer Cells by Activating the NGFR-AMPK-mTOR Pathway [PDF]

, 2022
Jiaqiao Li, Yameng Fan, Yan Zhang, Yamei Liu, Yan Yu, Mao Ma   +5 more
openalex   +1 more source

TCGA whole-transcriptome sequencing data reveals significantly dysregulated genes and signaling pathways in hepatocellular carcinoma [PDF]

, 2015
This study systematically evaluates the TCGA whole-transcriptome sequencing data of hepatocellular carcinoma (HCC) by comparing the global gene expression profiles between tumors and their corresponding nontumorous liver tissue. Based on the differential
Ho, DWH, Kai, AKL, Ng, IOL
core   +1 more source

Polymer-Encapsulated Schwannoma Cells Expressing Human Nerve Growth Factor Promote the Survival of Cholinergic Neurons after a Fimbria-Fornix Transection

Cell Transplantation, 1995
Many investigators have recently used genetically modified primary fibroblasts of fibroblast cell lines (e.g., 3T3, 208F, or BHK cells) to deliver recombinant nerve growth factor (NGF) into the CNS.
Malcolm Schinstine, Deborah M. Fiore, Shelley R. Winn, Dwaine F. Emerich   +3 more
doaj   +1 more source

Cutaneous lesions sensory impairment recovery and nerve regeneration in leprosy patients

Memorias do Instituto Oswaldo Cruz, 2012
It is important to understand the mechanisms that enable peripheral neurons to regenerate after nerve injury in order to identify methods of improving this regeneration.
Ximena Illarramendi, Emanuel Rangel, Alice Machado Miranda, Ana Claudia Ribeiro de Castro, Giselle de Oliveira Magalhães, Sérgio Luiz Gomes Antunes   +5 more
doaj   +1 more source

Author Correction: Reversal of pre-existing NGFR-driven tumor and immune therapy resistance [PDF]

, 2023
Julia Boshuizen, David W. Vredevoogd, Oscar Krijgsman, Maarten A. Ligtenberg, Stéphanie A. Blankenstein, Beaunelle de Bruijn, Dennie T. Frederick, Juliana C.N. Kenski, Mara Parren, Marieke Brüggemann, Max F. Madu, Elisa A. Rozeman, Ji‐Ying Song, Hugo M. Horlings, Christian U. Blank, Alexander C. J. van Akkooi, Keith T. Flaherty, Genevieve M. Boland, Daniel S. Peeper   +18 more
openalex   +1 more source