Results 11 to 20 of about 11,425 (225)
Differentiation of human embryonic stem cells into cells with corneal keratocyte phenotype. [PDF]
PLoS ONE, 2013 Corneal transparency depends on a unique extracellular matrix secreted by stromal keratocytes, mesenchymal cells of neural crest lineage. Derivation of keratocytes from human embryonic stem (hES) cells could elucidate the keratocyte developmental pathway
Audrey A Chan +8 more
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NGFR regulates stromal cell activation in germinal centers
Cell ReportsSummary: Nerve growth factor receptor (NGFR) is expressed by follicular dendritic cells (FDCs). However, the role of NGFR in the humoral response is not well defined.
Alberto Hernández-Barranco +18 more
doaj +7 more sources
Inhibition of circRNA NGFR promotes ferroptosis in gallbladder carcinoma cells
HeliyonBackground: Gallbladder carcinoma (GBC) is a formidably aggressive malignancy. Circular RNAs (circRNAs) play crucial regulatory roles in cancer. NGFR is a novel circRNA implicated in various types of cancers.
Desen Fan +5 more
doaj +3 more sources
iScience, 2023 Summary: We performed scRNA-seq/snATAC-seq of skeletal muscles post sciatic nerve transection to delineate cell type-specific patterns of gene expression/chromatin accessibility at different time points post-denervation.
Chiara Nicoletti +6 more
doaj +3 more sources
bFGF Upregulates the Expression of NGFR in PC12 Cells
Journal of Hard Tissue Biology, 2013 The reciprocal and highly regulated processes of cellular proliferation, cellular differentiation, and progression to a postmitotic state during embryogenesis generate the cellular diversity in the developing nervous system. Growth factors, in part, can regulate these proliferative or differentiation processes by analogous mechanisms.
Michiharu Shimosaka, Ujjal K. Bhawal
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Epigenetic Inactivation and Tumor-Suppressor Behavior of NGFR in Human Colorectal Cancer [PDF]
Molecular Cancer Research, 2014 Abstract The nerve growth factor receptor (NGFR/p75) is a potential tumor suppressor, but its role in colorectal cancer is unknown. Here, the hypermethylation status, biologic function, and clinical relevance were determined for p75NGFR in colorectal cancer.
Zuli Yang +11 more
openalex +4 more sources
Escape from NK cell tumor surveillance by NGFR-induced lipid remodeling in melanoma [PDF]
Science Advances, 2023 Metastatic disease is a major cause of death for patients with melanoma. Melanoma cells can become metastatic not only due to cell-intrinsic plasticity but also due to cancer-induced protumorigenic remodeling of the immune microenvironment. Here, we report that innate immune surveillance by natural killer (NK) cells is bypassed by human melanoma cells ...
Julian Hengsteler +11 more
openalex +3 more sources