Results 71 to 80 of about 11,425 (225)

Contributions of Cell-extrinsic and Cell-intrinsic Factors to the Differentiation of a Neural-crest-derived Neuroendocrine Progenitor Cell [PDF]

, 1990
A central question in developmental neurobiology concerns the mechanisms that generate cellular diversity in the vertebrate nervous system. Cell lineage analyses have established that many progenitor cells in the developing nervous system are multipotent
Anderson, D. J., Birren, S. J., Mori, N., Stein, R., Stemple, D., Vanderbergh, D. J., Wuenschell, C. W.   +6 more
core   +1 more source

Combinatorial expression of glial transcription factors induces Schwann cell‐specific gene expression in mouse embryonic fibroblasts

Developmental Dynamics, EarlyView.
Abstract Background Schwann cells provide peripheral nerve trophic support, myelinate axons, and assist in repair. However, Schwann cell repair capacity is limited by chronic injury, disease, and aging. Schwann cell reprogramming is a cellular conversion strategy that could provide a renewable cell supply to repair injured nerves.
Lauren Belfiore, Anjali Balakrishnan, Yacine Touahri, Dawn Zinyk, Humna Noman, Satoshi Okawa, Jeff Biernaskie, Carol Schuurmans   +7 more
wiley   +1 more source

Loss of YY1, a Regulator of Metabolism in Melanoma, Drives Melanoma Cell Invasiveness and Metastasis Formation

Frontiers in Cell and Developmental Biology, 2022
Deregulation of cellular metabolism through metabolic rewiring and translational reprogramming are considered hallmark traits of tumor development and malignant progression.
Ulf Guendisch, Benjamin Loos, Phil F. Cheng, Reinhard Dummer, Mitchell P. Levesque, Sandra Varum, Lukas Sommer   +6 more
doaj   +1 more source

530 Analysis of BRAF mutation and expression of NGFR and P16 in nevus and melanoma [PDF]

, 2021
Jianglong Feng, Wen Zeng, Hongyun Lu
openalex   +1 more source

NGF, TrkA-P and neuroprotection after a hypoxic event in the developing central nervous system [PDF]

, 2018
A decrease in the concentration of oxygen in the blood and tissues (hypoxia) produces important, sometimes irreversible, damages in the central nervous system (CNS) both during development and also postnatally.
Bogetti, María Eugenia, Fiszer de Plazas, Sara, Flores, Domingo Vladimir, Pozo Devoto, Victorio Martin, Rapacioli, Melina   +4 more
core   +1 more source

Tumor Organoids: Breakthroughs in Clinical Decision Making, Drug Development, and Translational Advances Beyond Conventional Models

Med Research, EarlyView.
ABSTRACT Tumor organoid models are revolutionizing cancer research by bridging the translational gap between conventional two‐dimensional cell cultures and animal models. This Editorial thoroughly explores the fundamental innovations of patient‐derived organoid technology.
Yimao Wu, Ruowei Sun, Gokhan Zengin, Shuai Ren, Meng‐Yao Li   +4 more
wiley   +1 more source

Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke

BMC Medical Genetics, 2018
Background Despite the important role of the nerve growth factor in the survival and maintenance of neurons in ischemic stroke, data regarding the relationships between variations in the encoding gene and stroke are lacking.
Ani Stepanyan, Roksana Zakharyan, Arsen Simonyan, Gohar Tsakanova, Arsen Arakelyan   +4 more
doaj   +1 more source

Nerve growth factor receptors in dementia [PDF]

, 2015
Background/aim: Nerve growth factor (NGF) promotes the survival and differentiation of sensory and sympathetic neurons. Several studies have found that certain neuropathological factors stimulate NGF receptor expression and release the truncated nerve ...
Mesripour, A., Messripour, M., Mohammadi, I., Nazarian, A.   +3 more
core   +1 more source

The sensory penis: A comprehensive immunohistological and ontogenetic exploration of human penile innervation

Andrology, EarlyView.
Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani, María Otero‐Alén, Juan Suárez‐Quintanilla, Marina Gándara‐Cortés, Tomás García‐Caballero, Rosalía Gallego, Lucía García‐Caballero   +6 more
wiley   +1 more source

Effect of amisulpride on the expression of serotonin receptors, neurotrophic factor BDNF and its receptors in mice with overexpression of the aggregation-prone [R406W] mutant tau protein

Вавиловский журнал генетики и селекции
Serotonin 5-HT7 receptors (5-HT7R) are attracting increasing attention as important participants in the mechanisms of Alzheimer’s disease and as a possible target for the treatment of various tau pathologies. In this study, we investigated the effects of
E. M. Kondaurova, A. A. Komarova, T. V. Ilchibaeva, A. Ya. Rodnyy, E. A. Zalivina, V. S. Naumenko   +5 more
doaj   +1 more source