Results 211 to 220 of about 169,956 (263)

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source

Extensive diversity and impact of drug-resistant HIV-1 variants in individuals with prior virologic failure. [PDF]

PLoS Pathog
Pillay M, Choudhary MC, Deo R, Naumenko S, Tamura TJ, Etemad B, Edelstein G, Khan A, Govender K, Govender S, Tzou P, Mick M, Herbert ZT, Muyindike W, Moosa MS, Brijkumar J, Sunpath H, McCluskey S, Chimukangara B, Manyana SC, Gounder L, Parboosing R, Francois KL, Shafer R, Ho Sui S, Pillay S, Marconi V, Siedner MJ, Moodley P, Msomi N, Li JZ.   +30 more
europepmc   +1 more source

Is p53 Immunohistochemistry a Reliable Indicator of <i>TP53</i> mutation? An NGS-based assessment in lung adenocarcinoma. [PDF]

Pak J Med Sci
Teoman G, Yilmaz ZS, Ersoz S, Aydin Mungan S.   +3 more
europepmc   +1 more source

Precise Reproductive Counseling Enabled by Long-Read Sequencing in a Case of a <i>F8</i> Intron 1 Inversion and Duplication. [PDF]

Appl Clin Genet
Yan Y, Jin P, Xu L, Ma Y, Dong M.
europepmc   +1 more source

HAT-PCR is non-inferior to NGS when quantifying measurable residual disease for myeloma. [PDF]

Br J Haematol
Hughes E, Blombery P, Kannan S, Khong T, Spencer A, Morley A.   +5 more
europepmc   +1 more source

Molecular characteristics, clonal relatedness and surgical outcomes of pulmonary mixed invasive mucinous and non-mucinous adenocarcinoma: a retrospective cohort study. [PDF]

Mol Biomed
Shi X, Wang Y, Yao N, Xue B, Guo L, Xu L, Zhu C, Qin G, Ying J, Liu Y, Li W.   +10 more
europepmc   +1 more source

Trends and Disparities in the Use of Next-Generation Sequencing in Patients With Cancer in the United States.

JAMA Netw Open
Hage Chehade C, Ozay ZI, Jo Y, Gebrael G, Sayegh N, Ostrowski M, Srivastava A, Garg D, Hardy T, Murdock EG, Narang A, Mathew Thomas V, Li H, Maughan BL, Roy S, Agarwal N, Swami U.   +16 more
europepmc   +1 more source

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Metabolism of NG,NG- and NG,NG-dimethylarginine in rats

Archives of Biochemistry and Biophysics, 1987
The metabolic fates of NG,NG-and NG,N'G-dimethylarginines in rats were investigated isotopically and novel metabolites, alpha-keto-delta-(N,N-dimethylguanidino)-and alpha-keto-delta-(N,N'-dimethylguanidino)valeric acids and gamma-(N,N-dimethylguanidino)-and gamma-(N,N'-dimethylguanidino)butyric acids were identified.
T, Ogawa, M, Kimoto, H, Watanabe, K, Sasaoka   +3 more
openaire   +2 more sources

Distribution of NG, NG-dimethylarginine in nuclear protein fractions

Biochemical and Biophysical Research Communications, 1977
Abstract Nuclear proteins have been fractionated into five distinct classes according to their extractability from rat liver nuclei at different pH and salt concentrations. The fractions have been analyzed for their amino acid composition which shows the presence of N G , N G -dimethylarginine, in sizable amount, in non-histone nuclear proteins (NHNP)
L C, Boffa, J, Karn, G, Vidali, V G, Allfrey   +3 more
openaire   +2 more sources