Results 241 to 250 of about 229,275 (305)

Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation

open access: yesAdvanced Materials Technologies, EarlyView.
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching   +9 more
wiley   +1 more source

Microneedles Fabrication by Substrate‐Independent Electrostretching and In‐Situ Focused Electrospray Deposition for Transdermal Drug Delivery

open access: yesAdvanced Materials Technologies, EarlyView.
A novel electrohydrodynamic platform integrating substrate‐independent in situ dried electrostretching (SI‐PIDES) and in situ focused electrospray deposition (IFED) enables mold‐free fabrication and precise drug coating of flexible core–sheath microneedle patches.
Ngoc Luan Mai   +7 more
wiley   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

A Novel Technique for Validating Copy Number Variants and Its Application in Familial Exudative Vitreoretinopathy. [PDF]

open access: yesHum Mutat
Zhang LL   +9 more
europepmc   +1 more source

Wireless Precise Manipulation of Tumor Spheroids Using a Millirobot Controlled by Permanent Magnetic Traps

open access: yesAdvanced Robotics Research, EarlyView.
A magnetic donut‐like millirobot is developed for label‐free pick‐and‐place of a tumor spheroid wirelessly controlled by a magnetic trap. Spheroids are important 3D multicellular culture systems that recapitulate key structural and functional features of native tissues.
Yue Gao   +8 more
wiley   +1 more source

Pre-operative circulating tumour DNA in high-risk primary cutaneous melanoma: prospective feasibility in molecular pathology. [PDF]

open access: yesActa Oncol
Obinah MPB   +7 more
europepmc   +1 more source

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