Results 61 to 70 of about 400,651 (265)
The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti +5 more
wiley +1 more source
Health Services and Delivery Research, 2015 Background: Over the life of the NHS, hospital services have been subject to continued reconfiguration. Yet it is rare for the reconfiguration of clinical services to be evaluated, leaving a deficit in the evidence to guide local reconfiguration of ...
Candace Imison +4 more
doaj +1 more source
Journal of the Royal Society of Medicine, 2016 I read the review of NICE by Professor Rawlins and was surprised that it does not mention at any point how much this bureaucratic process costs. I suspect it employs hordes of people and spends millions of pounds to produce guidance that usually seems to just tell us what we already know with a bit of stuff on quality-adjusted life years thrown in.
openaire +2 more sources
Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova +9 more
wiley +1 more source
Health Services and Delivery Research, 2014 Background: The search for causal links between human resource management (HRM) and organisational performance has dominated academic and practitioner debates for many years.
Martin Powell +4 more
doaj +1 more source
BMJ, 2008 Is the NHS a clapped out behemoth or the best gift the British people have ever given themselves?
openaire +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether myelin‐sensitive quantitative MRI reveals microstructural abnormalities in normal‐appearing cortex (NACtx) in myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), indicating that conventional MRI underestimates remission residual cortical injury.
Valentina Camera +20 more
wiley +1 more source
Health and Social Care Integration in Scotland: Evidence vs Rhetoric
International Journal of Integrated CareIn this perspective paper we use publicly-available data to show that, despite much positive rhetoric in support of reforms in Scotland to integrate health and social care, these reforms, in their current state, have failed to meet their stated ...
Cam Donaldson +3 more
doaj +1 more source
Health Technology Assessment, 2015 Background: Initial treatment for early breast cancer is usually either breast-conserving surgery (BCS) or mastectomy. After BCS, whole-breast external beam radiotherapy (WB-EBRT) is the standard of care. A potential alternative to post-operative WB-EBRT
Jo Picot +5 more
doaj +1 more source
Journal of the Royal Society of Medicine, 2005 Sixty years ago, the new National Health Service promised that a doctor would be assured ‘freedom... to pursue his professional methods in his own individual way, and not to be subject to outside clinical interference’.1 But after thirty years, the Chief Medical Officer, Sir George Godber, set out to define a ‘Cogwheel’ structure for the accountability
openaire +2 more sources