Results 131 to 140 of about 213,618 (247)

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Rational design and synthesis of Co(ii), Ni(ii) and Cu(ii) complexes bearing 1,2,4-triazole scaffold for biological applications. [PDF]

RSC Adv
Hassoon AA, Abulkhair HS, Ashour RH, Abdelsamea MM, Abdullah HO, Eldesoky MA, Shaban AR, John P, Ghaith EA.   +8 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

"Sonochemically synthesized Ag(I) and Ni(II) schiff base complexes as efficient visible-light photocatalysts for dye degradation with DFT insights." [PDF]

Sci Rep
Saleh AM, Mahdy AG, Hamed AA.
europepmc   +1 more source

Two ternary Ni(II) complexes: Bisglycinato(1,10-phenanthroline) Ni(II) trihydrate and Bisglycinato(2,2"™-bipyridine) Ni(II) trihydrate

, 1995
Acta Crystallographica Section ...
Skoulika, S., Michaelides, A., Aubry, A.
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Solvatochromic, spectroscopic, DFT calculations, antimicrobial and docking studies of new Fe(III), Co(II), and Ni(II) chelates containing 1,2,4-triazine. [PDF]

Sci Rep
Abdelrhman EM, Samy F, Adly OMI, Boshra M, Eid MF, Salah N.   +5 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Antimicrobial, antibiofilm, antioxidant activities and molecular docking of Schiff base and its complexes of Cu(II), Co(II), Ni(II), Mn(II) and UO₂(II). [PDF]

Sci Rep
Wahba RH, AbouElleef EM, Gomaa EA, Diab MA, Abou-Dobara MI, El-Zahed MM, El-Sonbati AZ.   +6 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source