Results 11 to 20 of about 146,744 (199)
Treatment of Idiopathic Membranous Nephropathy for Moderate or Severe Proteinuria: A Systematic Review and Network Meta-Analysis. [PDF]
Int J Clin Pract, 2022 Objective. Numerous studies have demonstrated that the efficacy of drugs differs in idiopathic membranous nephropathy (IMN) patients with moderate or high proteinuria. However, there is no systematic comparison confirming it. This network meta‐analysis (NMA) was performed to respectively compare the efficacy of ten IMN treatments in patients with ...
Chen M, Liu J, Xiong Y, Xu G.
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Angular-Inertia Regulated Stable and Nanoscale Sensing of Single Molecules Using Nanopore-In-A-Tube. [PDF]
Adv MaterThe study develops a nanopore‐in‐a‐tube (NIAT) device that precisely regulates molecule translocation in a funnel‐shaped nanopore by controlling the inertial angle and centrifugation speed in a centrifuge. This ensures stable signal readout with a high signal‐to‐noise ratio, enabling nanoscale sensing of single molecules.
Yang J +5 more
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Fkbp5 gene deletion: Circadian rhythm profile and brain proteomics in aged mice. [PDF]
Aging CellThis study investigates the circadian rhythm and proteomic profile of aged FKBP51 knockout mice. The absence of FKBP51 provided protection against stress‐mediated disruptions in circadian rhythms in a sex‐dependent manner. Proteomic changes in these mice showed brain region‐ and sex‐dependent alterations, with elevated levels of proteins like MYCBP2 ...
Gebru NT +10 more
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FKBP51: A Promising Therapeutic Target for Tauopathies [PDF]
Alzheimers DementAbstract Background Tau accumulation, a hallmark of Alzheimer’s disease, fuels cognitive decline and neuronal death. Our team identified FKBP51, a stabilizer of neurotoxic tau oligomers. Notably, FKBP51 levels increase with age and further in AD brains, where it is found associated with pathological tau.
Gebru N +4 more
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Appl Bionics Biomech, 2022 Background. Primary membranous nephropathy (MN), sometimes referred to as idiopathic membranous nephropathy (IMN), is a kind of MN whose pathogenesis is yet unclear. According to research reports, the incidence of IMN is about 9.8–26.8%, and it is on the rise. Methods.
Lu H, Shen J, Sun J, Sun J.
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Heterogeneous responses to corporate marginal tax rates: Evidence from small and large firms
Journal of Applied Econometrics, Volume 38, Issue 7, Page 1018-1047, November/December 2023., 2023 Summary Do small and large firms respond differently to tax cuts? Using new narrative measures of the exogenous variation in corporate marginal tax rates and a unique dataset of US manufacturing firms, we find that the investment of large firms is more sensitive to a marginal tax cut than that of small firms.
Ruhollah Eskandari, Morteza Zamanian
wiley +1 more source
A two‐stage Bayesian network model for corporate bankruptcy prediction
International Journal of Finance &Economics, Volume 27, Issue 1, Page 455-472, January 2022., 2022 Abstract We develop a Bayesian network (LASSO‐BN) model for firm bankruptcy prediction. We select financial ratios via the Least Absolute Shrinkage Selection Operator (LASSO), establish the BN topology, and estimate model parameters. Our empirical results, based on 32,344 US firms from 1961–2018, show that the LASSO‐BN model outperforms most ...
Yi Cao, Xiaoquan Liu, Jia Zhai, Shan Hua
wiley +1 more source
Topological Descriptors and Polynomials for Analysing the Structure of Antimony Telluride
Journal of Mathematics, Volume 2022, Issue 1, 2022., 2022 In a molecular network, molecules are correlated with numerical values, which are referred to as topological indices. The chemical and physical properties of chemical substances can be determined using topological indices. Mathematicians frequently use topological indices to calculate the strain energy, melting point, boiling temperature, distortion ...
Shahid Imran +5 more
wiley +1 more source
Computing Topological Indices and Polynomials of the Rhenium Trioxide
Journal of Mathematics, Volume 2022, Issue 1, 2022., 2022 In the study of mathematical chemistry and chemical graph theory, a topological index, also known as a connectivity index, is the arithmetical framework of a graph that specifies its topology and also graph invariant. These topological indices are used to model quantitative structure relationships (QSARs), which are connections between the work of ...
Shahid Imran +5 more
wiley +1 more source
Role of LEAFLESS, an AP2/ERF family transcription factor, in the regulation of trichome specialized metabolism. [PDF]
New PhytolSummary Acylsugars, specialized metabolites produced by trichomes of many solanaceous species, provide protection against biotic and abiotic stresses. Many acylsugar metabolic enzymes have been identified; however, regulatory factors remain unknown.
Mandal S, Rezenom YH, McKnight TD.
europepmc +2 more sources