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Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

open access: yesAdvanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck   +8 more
wiley   +1 more source
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A Simple Measure of Niche Breadth

Ecology, 1981
Niche breadths in animal and plant populations are often measured without regard to the relative frequencies of the various resources available to the organisms. Recent papers have provided more accurate indices for use when available resources can be quantified. These indices may lack wide applicability or simple biological interpretations. We suggest
Feinsinger, Peter   +2 more
openaire   +1 more source

On the Measurement of Niche Breadth and Overlap

Ecology, 1971
Measures of niche breadth and overlap that depend on the distribution of individual among resource states (ecological categories) should be independent of the relative abundance of the species and of the number of resource states considered. Such measures should also take into account the degree of distinctness of the resource states from the point of ...
Robert K, Colwell, Douglas J, Futuyma
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Niche Breadth Calculation Based on Discriminant Analysis

Ecology, 1982
Pyke, G. H. 1981. Optimal nectar production in a hummingbird-pollinated plant. Theoretical Population Biology 20:326-343. Reincke, D. C., and W. L. Bloom. 1979. Pollen dispersal in natural populations: a method for tracking individual grains. Systematic Botany 4:223-229. Schaal, B. A. 1975.
Beatrice Van Horne, R. Glenn Ford
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