Results 181 to 190 of about 139,272 (299)

Contrasting genetic diversity and ecological niche modelling of the montane grass mouse <i>Akodon montensis</i> in the south of the Atlantic Forest. [PDF]

R Soc Open Sci
Labaroni CA, Tarquino-Carbonell AP, Vera NS, Schneider RG, Buschiazzo LM, De Cena RV, García G, Chiappero MB, Marti DA, Lanzone C.   +9 more
europepmc   +1 more source

A Superhydrophobic 3D Cell Culture System Reveals the Mechanobiological Role of Cancer‐Associated Fibroblasts in Prostate Cancer Metastasis

Advanced Healthcare Materials, EarlyView.
A superhydrophobic 3D cell culture platform enables rapid and consistent formation of heterotypic tumor–stroma clusters, and reveals how physiological shear conditions influence metastatic signaling. Mechanical stimulation of cancer‐associated fibroblasts promotes sustained cytokine secretion and survival‐promoting pathways, showing how multicellular ...
Alexandria T. Carter, Abigail R. Fabiano, Ehsan Aalaei, Jason Deng, Dakota E. Rostant, Michael R. King   +5 more
wiley   +1 more source

A Physiological Microfluidic Blood–Brain‐Barrier Model for In Vitro Study of Nanoparticle Trafficking and Accumulation

Advanced Healthcare Materials, EarlyView.
A human microfluidic blood‐brain barrier (mBBB) model enables spatially resolved comparison of nanoparticle trafficking. Extracellular vesicles (EVs), liposomes, and nanoplastics exhibit distinct transport and disruption behaviors, revealing that membrane composition and uptake pathways govern BBB interaction.
Bryan B. Nguyen, Neona M. Lowe, Sophia Kellogg, Kuan‐Wei Huang, Hannah O'Toole, Elizabeth J. Hale, Venktesh S. Shirure, Bhupinder S. Shergill, Steven C. George, Randy P. Carney   +9 more
wiley   +1 more source

Genetic diversity hotspot at the edge of the species range: integrating plastome phylogeography with ecological niche modelling for the conservation of Ulmus glabra Huds. in the Italian peninsula. [PDF]

BMC Plant Biol
Villa S, Marchesini A, Torre S, Pepori AL, Pecori F, Ghelardini L, Selvaggi A, Sebastiani F, Santini A.   +8 more
europepmc   +1 more source

The liver metastatic niche: modelling the extracellular matrix in metastasis.

Dis Model Mech, 2021
Drew J, Machesky LM.
europepmc   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Quaternary Habitat Fluctuations and Demographic Dynamics in Turtles Inferred From Environmental Niche Modelling and Whole Genome Data. [PDF]

Mol Ecol Resour
Sozzoni M, Balacco J, Bellavita M, Brüniche-Olsen A, Formenti G, Jain N, Koo B, Mountcastle J, Palmada-Flores M, Trifonov V, Chelazzi G, Fratini S, Jarvis ED, Natali C, Nespoli D, Ciofi C, Iannucci A.   +16 more
europepmc   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

Using ecological niche modelling to identify the high-quality ecological areas of <i>Houttuynia cordata Thunb.</i> based on secondary metabolites content. [PDF]

Front Plant Sci
Zhang X, Zhou J, Xu H, Peng C, Meng F.
europepmc   +1 more source

Global distribution patterns and niche modelling of the invasive Kalanchoe × houghtonii (Crassulaceae). [PDF]

Sci Rep, 2020
Herrando-Moraira S, Vitales D, Nualart N, Gómez-Bellver C, Ibáñez N, Massó S, Cachón-Ferrero P, González-Gutiérrez PA, Guillot D, Herrera I, Shaw D, Stinca A, Wang Z, López-Pujol J.   +13 more
europepmc   +1 more source