Results 171 to 180 of about 519,778 (295)

Glucose and Glutamine Deprivation Promotes Breast Cancer Lung Metastasis via BRD4‐Dependent Enhancer Activation

open access: yesAdvanced Science, EarlyView.
To model a nutrient‐restricted tumor microenvironment, breast cancer cells were adapted to low glucose and glutamine levels. In the adapted cells, BRD4‐driven enhancer activation increases pro‐invasive EDN1 expression, facilitated by ATF3/c‐JUN and reinforced by enhancer RNA.
Poshan Yugal Bhattarai   +4 more
wiley   +1 more source

Niche Overlap in Forest Tree Species Precludes a Positive Diversity-Productivity Relationship. [PDF]

open access: yesPlants (Basel)
Blackstone KMS   +7 more
europepmc   +1 more source

Correction to: Network structure of resource use and niche overlap within the endophytic microbiome. [PDF]

open access: yesISME J, 2022
Michalska-Smith M   +8 more
europepmc   +1 more source

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

open access: yesAdvanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen   +7 more
wiley   +1 more source

Soil Aggregates and Fertilizer Treatments Drive Bacterial Interactions via Interspecies Niche Overlap. [PDF]

open access: yesMicrobiol Spectr, 2022
Xiong X   +7 more
europepmc   +1 more source

D4F‐Functionalized Ceria Nanozyme‐CasRx Platform Suppresses STING and Reprograms the Renal Immune Niche in Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
D4F‐functionalized ceria nanozyme–CasRx nanoparticles preferentially target renal macrophages through SR‐B1‐mediated uptake in ischemia–reperfusion injury. Ceria scavenges excessive ROS, while CasRx silences STING signaling, shifting macrophages toward a less inflammatory, pro‐resolving state and increasing the proportion of regulatory T cells.
Weibo Chen   +11 more
wiley   +1 more source

Network structure of resource use and niche overlap within the endophytic microbiome. [PDF]

open access: yesISME J, 2022
Michalska-Smith M   +8 more
europepmc   +1 more source

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