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Colorimetry of Total Phenolics with Phosphomolybdic-Phosphotungstic Acid Reagents

American Journal of Enology and Viticulture, 1965
Several details of the assay of total phenolic substances have been investigated and an improved procedure developed. The improvements include the use of Folin-Ciocalteu reagent rather than the Folin-Denis reagent, gallic acid as a reference standard ...
V. L. Singleton, J. Rossi
semanticscholar   +1 more source

Nucleic Acid Therapeutics: Successes, Milestones, and Upcoming Innovation

Nucleic Acid Therapeutics
Nucleic acid-based therapies have become the third major drug class after small molecules and antibodies. The role of nucleic acid-based therapies has been strengthened by recent regulatory approvals and tremendous clinical success.
Jillian Belgrad   +2 more
semanticscholar   +1 more source

Hepatotoxicity Reduction Profiles of Antisense Oligonucleotides Containing Amido-Bridged Nucleic Acid and 2′-O,4′-C-Spirocyclopropylene Bridged Nucleic Acid

Nucleic Acid Therapeutics
Amido-bridged nucleic acid (AmNA) and a 2′-O,4′-C-spirocyclopropylene bridged nucleic acid (scpBNA) are bridged nucleic acid analogs with high binding affinity toward complementary strands along with high nuclease resistance.
Takaaki Kawanobe   +8 more
semanticscholar   +1 more source

Peptide Nucleic Acid-Mediated Regulation of CRISPR-Cas9 Specificity

Nucleic Acid Therapeutics
Although CRISPR-Cas9 gene therapies have proven to be a powerful tool across many applications, improvements are necessary to increase the specificity of this technology.
Kelly E W Carufe   +2 more
semanticscholar   +1 more source

Predicting subcellular localization of proteins based on their N-terminal amino acid sequence.

Journal of Molecular Biology, 2000
O. Emanuelsson   +3 more
semanticscholar   +1 more source

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