Results 51 to 60 of about 6,570 (287)
Advanced Science, EarlyView.. ABSTRACT Neuroinflammation driven by microglial activation is a defining feature of Alzheimer's disease (AD), yet the molecular mechanisms sustaining this proinflammatory state remain unclear. Here, we identify the deubiquitinase OTUD7B as a critical regulator of microglial activation and AD pathology.
Luyao Li +15 more
wiley +1 more source
Advanced Science, EarlyView.Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li +8 more
wiley +1 more source
Creation of Internet Relay Chat Nicknames and Their Usage in English Chatroom Discourse [PDF]
Linguistik Online, 2011 In a chat discourse it is not always clear who is chatting with whom; automatic discourse analysis is especially problematic. It is important to identify the users' nicknames in the written discourse to find out the receivers of the chat messages.
Ecker, Robert
doaj +3 more sources
The Malditas, The Filipinas, and The Azkals
NamesNicknames in sports can serve a wide range of social and semantic functions. Assigning nicknames to athletes and teams can allow fans to identify with them.
Satwinder Rehal, Inez Z. Ponce de Leon
doaj +1 more source
Advanced Science, EarlyView.Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu +11 more
wiley +1 more source
Nicknames for Group Signatures
Nicknames for Group Signatures (NGS) is a new signature scheme that extends Group Signatures (GS) with Signatures with Flexible Public Keys (SFPK). Via GS, each member of a group can sign messages on behalf of the group without revealing his identity, except to a designated auditor.
Guillaume Quispe +2 more
openaire +3 more sources
, 2015 University of Minnesota Ph.D. dissertation. April 2015. Major: Germany Studies. Advisors: Anatoly Liberman, Kaaren Grimstad. 1 computer file (PDF); v, 273 pages, appendix p.
Peterson, Paul R.
core
A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers
Advanced Science, EarlyView.Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels +2 more
wiley +1 more source
Nicknames and Women Professional Baseball Players
Names, 1990 Although women in the general population tend to have fewer nicknames than men, women baseball players in the All-American Girls Baseball League, 1943–1954, were as likely as male baseball players to have public nicknames. This high percentage may be the
Brenda S. Wilson, James K. Skipper
doaj +1 more source