Results 21 to 30 of about 140,458 (343)

Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana

Communications Biology, 2022
The biosynthesis of strictosidine, a key intermediate of monoterpene indole alkaloids, was successfully reconstructed in Nicotiana benthamiana, demonstrating the potential of Nicotiana benthamiana as a bioproduction chassis for small molecules.
Quentin M. Dudley, Seohyun Jo, Delia Ayled Serna Guerrero, Monika Chhetry, Mark A. Smedley, Wendy A. Harwood, Nathaniel H. Sherden, Sarah E. O’Connor, Lorenzo Caputi, Nicola J. Patron   +9 more
doaj   +1 more source

Tomato resistance to Alternaria stem canker: localization in host genotypes and functional expression compared to non-host resistance [PDF]

, 1989
The Alternaria stem canker resistance locus (Asc-locus), involved in resistance to the fungal pathogen Alternaria alternata f. sp. lycopersici and in insensitivity to host-specific toxins (AAL-toxins) produced by the pathogen, was genetically mapped on ...
Griend, E.G. van de,, Hille, J.,, Nijkamp, H.J.J.,, Tiersma, J.B.,, Witsenboer, H.M.A.,   +4 more
core   +2 more sources

Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus [PDF]

, 2020
Rhabdoviruses are enveloped negative-sense RNA viruses that have numerous biotechnological applications. However, recovering plant rhabdoviruses from cDNA remains difficult due to technical difficulties such as the need for concurrent in planta ...
Drake, P, Ibrahim, AEC, Ma, J, Van Dolleweerd, CJ   +3 more
core   +1 more source

Current Status and De Novo Synthesis of Anti-Tumor Alkaloids in Nicotiana

Metabolites, 2023
Alkaloids are the most diversified nitrogen-containing secondary metabolites, having antioxidant and antimicrobial properties, and are extensively used in pharmaceuticals to treat different types of cancer.
Md. Ahsan Habib, Md. Mobinul Islam, Md. Mukul Islam, Md. Mohidul Hasan, Kwang-Hyun Baek   +4 more
doaj   +1 more source

Next generation sequencing analysis reveals a relationship between rDNA unit diversity and locus number in Nicotiana diploids [PDF]

, 2012
© 2012 Matyášek et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and ...
Fulnecek, J, Grandbastien, M-A, Kovarik, A, Leitch, A, Macas, J, Matyasek, R, Nichols, R, Renny-Byfield, S   +7 more
core   +5 more sources

Most AAL Toxin-Sensitive Nicotiana Species are Resistant to the Tomato Fungal Pathogen Alternaria alternata f. sp. lycopersici

Molecular Plant-Microbe Interactions, 2001
The phytopathogenic fungus Alternaria alternata f. sp. lycopersici produces AAL toxins required to colonize susceptible tomato (Lycopersicon esculentum) plants. AAL toxins and fumonisins of the unrelated fungus Fusarium moniliforme are sphinganine-analog
Bas F. Brandwagt, Tarcies J. A. Kneppers, Gerard M. Van der Weerden, H. John J. Nijkamp, Jacques Hille   +4 more
doaj   +1 more source

Comparative Chloroplast Genomes of Nicotiana Species (Solanaceae): Insights Into the Genetic Variation, Phylogenetic Relationship, and Polyploid Speciation

Frontiers in Plant Science, 2022
Nicotiana L. is a genus rich in polyploidy, which represents an ideal natural system for investigating speciation, biodiversity, and phytogeography.
Shuaibin Wang, Shuaibin Wang, Junping Gao, Haoyu Chao, Zhaowu Li, Wenxuan Pu, Yaofu Wang, Ming Chen   +7 more
doaj   +1 more source

Virus-induced gene silencing database for phenomics and functional genomics in Nicotiana benthamiana [PDF]

, 2018
Virus-induced gene silencing (VIGS) is an important forward and reverse genetics method for the study of gene function in many plant species, especially Nicotiana benthamiana.
Chakravarthy, Suma, Chang, Junil, Del Pozo, Olga, Dinesh-Kumar, Savithramma P, Doraiswamy, Vanthana, Lee, Hee-Kyung, Liu, Yule, Martin, Gregory B, Mysore, Kirankumar S, Ramegowda, Venkategowda, Ryu, Choong-Min, Senthil-Kumar, Muthappa, Van Eck, Joyce, Wang, Keri, Wang, Mingyi, Xu, Ping   +15 more
core   +2 more sources

The impact of genome evolution on the allotetraploid Nicotiana rustica – an intriguing story of enhanced alkaloid production

BMC Genomics, 2018
Background Nicotiana rustica (Aztec tobacco), like common tobacco (Nicotiana tabacum), is an allotetraploid formed through a recent hybridization event; however, it originated from completely different progenitor species.
N. Sierro, J. N. D. Battey, L. Bovet, V. Liedschulte, S. Ouadi, J. Thomas, H. Broye, H. Laparra, A. Vuarnoz, G. Lang, S. Goepfert, M. C. Peitsch, N. V. Ivanov   +12 more
doaj   +1 more source

Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco [PDF]

, 2014
The proposed clinical trial in Africa of VRC01, a potent broadly neutralizing antibody (bNAb) capable of neutralizing 91% of known HIV-1 isolates, raises concerns about testing a treatment which will be too expensive to be accessible by the most ...
EMEA, Montefiori D.C., Pabst M., Pegu A., WHO   +4 more
core   +1 more source