Results 191 to 200 of about 303,294 (304)

Canal Cholesteatoma Presentation and Management: A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To evaluate current understanding of external auditory canal cholesteatoma (EACC), its symptomatic burden, clinical features, diagnostic approach, and management strategies to reduce delays in diagnosis. Data Sources PubMed, CINAHL, COCHRANE Library, and SCOPUS.
Angelica M. Walker, Matthew Cheung, Shaun A. Nguyen, Kate Bonham, Erin A. Harvey, Robert F. Labadie, Ted A. Meyer   +6 more
wiley   +1 more source

Perioperative Opioid Use and Risk of Persistent Use After Common Otolaryngologic Procedures

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective The objective of this study was to evaluate the incidence of perioperative opioid prescription and the development of new persistent opioid usage in patients prescribed perioperative opioids for common otolaryngological procedures. Study Design Retrospective cohort study. Setting TriNetX US Collaborative Research Network. Methods The
Michael Liu, Austin Lee, Salim Hayek, Shawn Li   +3 more
wiley   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Bioinformatics‐Driven Design and Evaluation of Recombinant Multi‐Epitope Immunogens Derived From Snake Venom Toxins as Potential Antivenom Candidates

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Snakebite envenomation is a major public health concern, particularly in low‐ and middle‐income regions where access to safe and effective antivenoms is limited. Traditional antivenoms, derived from immunization with crude venom, often trigger adverse reactions and lack specificity against key venom components.
Hanan Maoz, Amir Elalouf
wiley   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, EarlyView.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source

Seedling resistance and chemical defenses against Psylliodes chrysocephala: the roles of seed age and sinapinic acid in Sinapis alba and Brassica napus

Pest Management Science, EarlyView.
The cabbage stem flea beetle (Psylliodes chrysocephala) is a major pest of winter oilseed rape (Brassica napus). We tested B. napus and Sinapis alba seedlings for feeding resistance and underlying chemical defenses. S. alba was least damaged, while metabolite profiles revealed resistance‐linked compounds, highlighting breeding potential for insect ...
Daniel Rüde, Samantha M Cook, Bernd Ulber, Tobias Pöhnl, Michael Rostás   +4 more
wiley   +1 more source

Characterising Patient Pathways Prior to the Diagnosis of Interstitial Lung Disease

Respirology, EarlyView.
ABSTRACT Background and Objective Interstitial lung diseases (ILDs) lead to breathlessness, cough, deteriorating quality of life and early death. Patients are typically diagnosed late in their disease course when existing lung damage cannot be reversed.
Caitlin C. Fermoyle, John Townend, Vidya Navaratnam, Nicole Goh, Francesca Gonnelli, Neva Eleangovan, Ursie Smith, Heath Heatley, Victoria Carter, David B. Price, Richard Hubbard, Tamera J. Corte   +11 more
wiley   +1 more source

Research on sleep quality and influencing factors among medical staff in a tertiary hospital in Anhui Province, China

Sleep Research, EarlyView.
To assess sleep quality and identify key influencing factors among medical staff in a tertiary hospital to support health policy development. Conducted in July 2024 using validated scales: Pittsburgh Sleep Quality Index (PSQI); Depression, Anxiety, and Stress Scale‐21; and Assessed: sleep quality, latency, disturbances, and daytime dysfunction.
Xiao‐Ying Jin, Ting Jiang, Ri‐Hong Wei, Meng‐Dan Chu, Han Li, Shan Zhang, Zeng‐Feng Su   +6 more
wiley   +1 more source

Integrating Pain Assessment in Nicotine and Tobacco Research and Treatment to Improve Cessation Outcomes. [PDF]

Nicotine Tob Res
Bagdas D, Powers JM, Rubenstein D, Sweitzer MM, Ditre JW, Weinberger AH.   +5 more
europepmc   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

Small, EarlyView.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi, Tijana Maric, Isidro Badillo‐Ramírez, Juliane Fjelrad Christfort, Matteo Tollemeto, Carmen Milan Guimera, Casper Nisula, Giulia Zappalá, Laura De Vittorio, Marta Rubio‐Huertas, Sungyeong Kim, Ziqiao Li, Morten Bo Søndergaard Svendsen, Zhongyang Zhang, Anja Boisen   +14 more
wiley   +1 more source