Results 191 to 200 of about 42,935 (312)

Different doses, durations and modes of delivery of nicotine replacement therapy for smoking cessation. [PDF]

open access: yesCochrane Database Syst Rev, 2023
Theodoulou A   +8 more
europepmc   +1 more source

A Randomized Crossover Clinical Study to Assess the Effect of Oral Nicotine Pouches Used for Different Durations on Plasma Nicotine Pharmacokinetics in Healthy Oral Pouch Consumers

open access: yesThe Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.
Abstract Oral nicotine pouches (NPs), although addictive and not risk‐free, have potential application for a tobacco harm reduction approach. This study aims to further characterize their ability to deliver nicotine effectively. This randomized seven‐way crossover PK study in healthy oral pouch consumers evaluated 11 and 20 mg NPs used for 10, 20, and ...
David Azzopardi   +6 more
wiley   +1 more source

Testing oral nicotine pouches versus nicotine replacement therapy for cigarette harm reduction in Appalachia: The ARISE study protocol. [PDF]

open access: yesPLoS One
Wermert A   +10 more
europepmc   +1 more source

Trends in Over-the-Counter Nicotine Replacement Therapy Sales, U.S., 2017‒2020. [PDF]

open access: yesAm J Prev Med, 2023
Trigger S   +5 more
europepmc   +1 more source

Olanzapine Attenuates Cue-elicited Craving for Tobacco

open access: yes, 2004
Rationale: Recent biological conceptualizations of craving and addiction have implicated mesolimbic dopamine activity as a central feature of the process of addiction. Imaging, and pharmacological studies have supported a role for dopaminergic structures
Hutchinson, Kent E   +5 more
core  

Critical evaluation of real‐world evidence of repurposable medicines in the Alzheimer's disease drug development pipeline using a target trial emulation

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 1, January/March 2026.
Abstract INTRODUCTION Repurposing Food and Drug Administration (FDA)‐approved drugs could accelerate treatment development for Alzheimer's disease (AD). METHODS Using the MarketScan claims database (2011 to 2020), we applied a trial emulation approach in two base cohorts: (1) individuals with mild cognitive impairment (MCI cohort) and (2) individuals ...
Reina Tonegawa‐Kuji   +10 more
wiley   +1 more source

Risk of Stroke in Patients With Schizophrenia, Bipolar Disorder, and Major Depressive Disorder: A Cohort Study of 183,504 Subjects

open access: yesActa Psychiatrica Scandinavica, Volume 153, Issue 1, Page 54-64, January 2026.
ABSTRACT Background Major psychiatric disorder, including schizophrenia, bipolar disorder, and major depressive disorder, has been individually associated with increased risk of stroke. However, few studies have directly compared the stroke risk across these diagnostic groups within a unified cohort framework while accounting for stroke subtypes and ...
Mao‐Hsuan Huang   +8 more
wiley   +1 more source

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