Results 91 to 100 of about 268,612 (162)

Identification of TREK channels in mouse intracardiac ganglion neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Role of TWIK‐related K+ (TREK) channels in intracardiac ganglion neurons. CD‐1 mice were used to establish primary cultures of intracardiac neurons for immunochemical characterization and patch‐clamp electrophysiology. Intracardiac neurons express functional TREK channels, which modulate neuronal excitability by regulating ...
Ana Campos‐Rios, Salvador Herrera‐Perez, Manuela Rodriguez‐Castañeda, Diego Ameal‐Tedin, Marta Alvarez‐Rodriguez, David Blanco‐Remesar, Ainhoa Rodriguez‐Tebar, Encarnación De Miguel, Ana Covelo, J. Antonio Lamas   +9 more
wiley   +1 more source

Nogo-B attenuates vascular calcification by activating NRF2-SLC7A11 to enhance antioxidant defense

Redox Biology
Objective: Vascular calcification (VC), characterized by abnormal calcium salts buildup in blood vessels, greatly raises the risk of adverse cardiovascular events. However, the mechanisms behind VC are not fully understood.
Dong Liang, Wenwen Zhang, Hongyu Zhang, Tingting Zhang, Jialing Ma, Ziyi Chen, Yuanyuan Wang, Lele Song, Wentao Huang, Suowen Xu, Hui Jiang, Xiang Kong, Danfeng Zhang, Ran Tao, Hao Hu, Jianyuan Pan, Xiaoxiao Yang, Qing Robert Miao, Yuanli Chen   +18 more
doaj   +1 more source

The use of real‐world data in health services research for dementia care: A scoping review

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 4, December 2026.
Abstract Health services research (HSR) is critical to informing dementia care and often relies on real‐world data (RWD); however, RWD use in HSR has not been systematically mapped in the United States. Following previous researchers and Preferred Reporting Items for Systematic Reviews and Meta‐Analyses extension for Scoping Reviews (PRISMA‐ScR ...
Ashley Kuzmik, Arpita Tripathi, Laura M. Block, Oluwagbemiga Oyinlola, Pedro JDMR Pinho, Zahra Rahemi, Pallavi Tyagi, Lycia Tramujas Vasconcellos Neumann   +7 more
wiley   +1 more source

The influence of salt formation on electrostatic and compression properties of flurbiprofen salts [PDF]

, 2013
Salt formation is an effective method of improving physicochemical properties of acidic and basic drugs. The selection of a salt form most suitable for drug development requires a well-designed screening strategy to ensure various issues are addressed in
Conway, Barbara R, Laity, Peter R., Šupuk, Enes, Asare-Addo, Kofi, Panchmatia, Pooja M., Ghori, Muhammad U., Ghori, Muhammad U.; id_orcid, Conway, Barbara R.; id_orcid   +7 more
core   +1 more source

The novel regulatory influence of Argonaute 1 on messenger RNA 5‐methylcytosine modification in Arabidopsis thaliana

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract 5‐Methylcytidine (m5C) modifications play a critical role in RNA metabolism. TRM4B (tRNA‐specific methytransferase 4B) is the only known component of the plant m5C machinery that mediates mRNA (messenger RNA) methylation. To date, no regulators governing site‐specific m5C modifications have been identified, apart from several degenerated ...
Zedi Feng, Xiu Yin, Zhifang Jiang, Jia Yao, Yiling Dong, Xiaoxia Ma, Yijun Meng   +6 more
wiley   +1 more source

Nicotine and carbonyl emissions from popular electronic cigarette products: Correlation to liquid composition and design characteristics [PDF]

, 2018
Introduction: Available in hundreds of device designs and thousands of flavors, electronic cigarette (ECIG) may have differing toxicant emission characteristics.
El-Hellani, Ahmad, Baalbaki, Rima, Malek, Nathalie J., Nakkash, Rima T., Talih, Soha, Karaoghlanian, Nareg, Saliba, Najat A., El-Hage, Rachel, Shihadeh, Alan Louis, Salman, Rola   +9 more
core   +1 more source

Effects of bioinsecticide exposure route on aphids and their natural enemies in oilseed rape

Pest Management Science, Volume 82, Issue 11, Page 10625-10636, November 2026.
Fatty acids, silicone polymers and surfactants reduced aphid numbers but caused natural enemy mortality under direct exposure, while minimal residual activity suggests potential for targeted, compatible use in integrated pest management. Abstract BACKGROUND Myzus persicae Sulzer and Brevicoryne brassicae L.
Aimee J. Tonks, Tom W. Pope, Simon Cooper, Joe M. Roberts   +3 more
wiley   +1 more source

Effects of user puff topography, device voltage, and liquid nicotine concentration on electronic cigarette nicotine yield: Measurements and model predictions [PDF]

, 2015
Introduction: Some electronic cigarette (ECIG) users attain tobacco cigarette-like plasma nicotine concentrations while others do not. Understanding the factors that influence ECIG aerosol nicotine delivery is relevant to regulation, including product ...
Eissenberg, Thomas E., El-Hellani, Ahmad, Baalbaki, Rima, Talih, Soha, Karaoghlanian, Nareg, Saliba, Najat A., Balhas, Zainab, Shihadeh, Alan Louis, Salman, Rola   +8 more
core   +1 more source

Lysine Requirements in Starter‐Phase Japanese Quail (Coturnix japonica) Through Dose–Response Modelling: Interactions With Dietary Protein Level

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
In starter Japanese quail, optimal lysine requirements (1.32%–1.42%) depend on dietary crude protein level. Supplementation at 1.4% maximizes body weight gain, protein efficiency, and breast yield, while oversupply (1.55%) impairs performance. Linear broken‐line modelling provides the most reliable requirement estimates for precision feeding.
Hamid Valizadeh, Mehdi Taghinejad‐Roudbaneh, Ruhollah Kianfar   +2 more
wiley   +1 more source

Protease and Phytase Alleviate Digestive Limitations of Canola Seed in Broiler Chickens

Veterinary Medicine and Science, Volume 12, Issue 6, November 2026.
Protease and phytase, especially in combination, counteracted the digestive limitations of 10% canola seed in broiler diets by improving nutrient utilisation, intestinal health, microbial balance, digesta viscosity, bone quality and growth performance.
Ramazan Sheikh‐Nazari, Kaveh Jafari‐Khorshidi, Mohammad Ali Jafari   +2 more
wiley   +1 more source