Results 161 to 170 of about 60,608 (292)

Trend Analysis of Medically Related Osteonecrosis of the Jaw in the United States Using US National Inpatient Data From 2016 to 2022

Journal of Public Health Dentistry, EarlyView.
ABSTRACT Objectives This study presents a trend analysis of Medication‐Related Osteonecrosis of the Jaw (MRONJ) using US National Inpatient Sample (NIS) data from 2016 to 2022, providing insights into its epidemiology, comorbidities, and economics.
N. Sheshashayee, M. B. Rao, E. Holmes, D. G. Krishnan   +3 more
wiley   +1 more source

Nicotinic acid protects against hepatic ischemia-reperfusion injury via suppressing mitochondrial damage-induced ferroptosis. [PDF]

Liver Res
Zeng Q, Sun Y, Lei M, Liu Z, Yan X, Li R, Zheng J, Zha J, Zhang L, Guan X, Yao J.   +10 more
europepmc   +1 more source

Expanding the Myxochelin Natural Product Family by Nicotinic Acid Containing Congeners. [PDF]

Molecules, 2021
Frank NA, Széles M, Akone SH, Rasheed S, Hüttel S, Frewert S, Hamed MM, Herrmann J, Schuler SMM, Hirsch AKH, Müller R.   +10 more
europepmc   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

The nicotinamide hypothesis revisited-plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione. [PDF]

FEBS Lett
Berglund T, Ohlsson AB.
europepmc   +1 more source

Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. [PDF]

Exp Neurol, 2021
Sasaki Y, Zhu J, Shi Y, Gu W, Kobe B, Ve T, DiAntonio A, Milbrandt J.   +7 more
europepmc   +1 more source

Pharmacokinetics and Safety of a Single Subcutaneous or Intramuscular Dose of Ketamine in Healthy Horses

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Pharmacokinetics (PK) of intramuscular (IM) and subcutaneous (SC) ketamine in horses has not been described. This study aimed to evaluate the PK and safety of ketamine and its metabolites after a single SC or IM administration. In Phase 1, two horses received 0.5 or 1 mg/kg of ketamine via SC and IM routes.
Ana Rangel, Debra C. Sellon, Macarena G. Sanz, Erin Pinnell, Zuzanna M. Pietras, Nicolas F. Villarino   +5 more
wiley   +1 more source

CD38 mediates nicotinamide mononucleotide base exchange to yield nicotinic acid mononucleotide. [PDF]

J Biol Chem
Madawala R, Banks JL, Hancock SE, Quek LE, Turner N, Wu LE.   +5 more
europepmc   +1 more source

The ratio of nicotinic acid to nicotinamide as a microbial biomarker for assessing cell therapy product sterility. [PDF]

Mol Ther Methods Clin Dev, 2022
Huang J, Cui L, Natarajan M, Barone PW, Wolfrum JM, Lee YH, Rice SA, Springs SL.   +7 more
europepmc   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source