Results 31 to 40 of about 6,176 (139)

An Update on the Recent Diagnostic Modalities of SARS-CoV-2: A Review [PDF]

Journal of Clinical and Diagnostic Research, 2023
The pandemic of respiratory viral pneumonia initiated as an outbreak during December 2019, at the Hubei region, China. The demanding research work conducted by the scientific community across the globe identified the causative agent as Severe Acute ...
Marie Victor Pravin Charles, Arunava Kali, Santhanam Vidyalakshmi   +2 more
doaj   +1 more source

Antiviral activity of K22 against members of the order Nidovirales

Virus Research, 2018
Recently, a novel antiviral compound (K22) that inhibits replication of a broad range of animal and human coronaviruses was reported to interfere with viral RNA synthesis by impairing double-membrane vesicle (DMV) formation (Lundin et al., 2014). Here we assessed potential antiviral activities of K22 against a range of viruses representing two (sub ...
Rappe, J.C.F., Wilde, A. de, , H. di, Muller, C., Stalder, H., V'kovski, P., Snijder, E., Brinton, M.A., Ziebuhr, J., Ruggli, N., Thiel, V.   +10 more
openaire   +3 more sources

On Classification and Taxonomy of Coronaviruses (Riboviria, Nidovirales, Coronaviridae) with Special Focus on Severe Acute Respiratory Syndrome-Related Coronavirus 2 (SARS-CoV-2)

Mathematical Biology and Bioinformatics, 2022
Coronaviruses are highly virulent and therefore important human and veterinary pathogens worldwide. This study presents the first natural hierarchical classification of Coronaviridae. We also demonstrate a “one-step” solution to incorporate the principles of binomial (binary) nomenclature into taxonomy of Coronaviridae. We strongly support the complete
E.V. Mavrodiev, M.L. Tursky, N.E. Mavrodiev, L. Schroder, A.P. Laktionov, M.C. Ebach, D.M. Williams   +6 more
openaire   +1 more source

Nidovirales

, 2008
Nidoviruses form a phylogenetically compact but diverse group of enveloped positive-stranded RNA viruses with the largest RNA genome known. They infect a broad range of hosts, including humans, other mammals, birds, fish, and shrimp. Nidovirus infection starts by binding to a receptor on the cell surface, and fusion of the viral and cellular membranes ...
Enjuanes, L., Gorbalenya, A.E., De Groot, R.J., Cowley, J.A., Ziebuhr, John, Snijder, E.J.   +5 more
openaire   +2 more sources

A bipartite hypovirus is the link to the emergence of the mega-hypoviruses carrying helicases from nidovirales

, 2023
Abstract of a talk presented at the V-International Mycovirus Symposium held in Gargnano, Italy May 30th-June2nd 2022.
, Forgia, Colariccio, , Picarelli, , Rivas, , Turina   +4 more
openaire   +1 more source

NUCLEAR LOCALIZATION SIGNAL PEPTIDES (NLS) AND THEIR ROLE IN VIRAL PATHOGENICITY

Annals of Mechnikov's Institute, 2020
The review provides data about nuclear localization signal peptides (NLS) and their function in the cell, incl. with a viral infection process. The binding, penetration, assembly, and budding of viruses are currently being intensively studied in many ...
Nosalskaya, Tatiana Nikolaevna , Martynov, Artur Viktorovich , Bomko, Tatiana Vasilievna   +2 more
doaj   +3 more sources

Biology and Pathogenesis of SARS-CoV-2: Understandings for Therapeutic Developments against COVID-19

Pathogens, 2021
Coronaviruses are positive sense, single-stranded, enveloped, and non-segmented RNA viruses that belong to the Coronaviridae family within the order Nidovirales and suborder Coronavirinae.
Homa Nath Sharma, Charity O. D. Latimore, Qiana L. Matthews   +2 more
doaj   +1 more source

Antiviral activity of carbohydrate-binding agents against Nidovirales in cell culture

Antiviral Research, 2007
Coronaviruses are important human and animal pathogens, the relevance of which increased due to the emergence of new human coronaviruses like SARS-CoV, HKU1 and NL63. Together with toroviruses, arteriviruses, and roniviruses the coronaviruses belong to the order Nidovirales.
van der Meer, F.J.U.M., de Haan, C.A.M., Schuurman, N.M., Haijema, B.J., Peumans, W.J., van Damme, E.J., Delputte, P.L., Balzarini, J., Egberink, H.F.   +8 more
openaire   +2 more sources

An Insect Nidovirus Emerging from a Primary Tropical Rainforest

mBio, 2011
Tropical rainforests show the highest level of terrestrial biodiversity and may be an important contributor to microbial diversity. Exploitation of these ecosystems may foster the emergence of novel pathogens.
Florian Zirkel, Andreas Kurth, Phenix-Lan Quan, Thomas Briese, Heinz Ellerbrok, Georg Pauli, Fabian H. Leendertz, W. Ian Lipkin, John Ziebuhr, Christian Drosten, Sandra Junglen   +10 more
doaj   +1 more source

Viral Instant Mutation Viewer: A Tool to Speed Up the Identification and Analysis of New SARS-CoV-2 Emerging Variants and Beyond

Viruses, 2023
The appearance of genetic variants impacts vaccination efficiency and therapeutic options, generating a need to map and relate mutations observed in the proteome and the genome.
Vincent Wilde, Bruno Canard, François Ferron   +2 more
doaj   +1 more source