Results 101 to 110 of about 24,478,248 (209)

c-Abl/TFEB Pathway Activation as a Common Pathogenic Mechanism in Lysosomal Storage Diseases: Therapeutic Potential of c-Abl Inhibitors

Antioxidants
Lysosomal storage diseases (LSDs) are characterized by the accumulation of undegraded substrates within lysosomes, often associated with oxidative stress and impaired lysosomal function. In this study, we investigate the role of the c-Abl/TFEB pathway in
Miguel V. Guerra, Juan Castro, Antonio Moreno, Elisa Balboa, Juan J. Marugan, Alejandra R. Alvarez, Silvana Zanlungo   +6 more
doaj   +1 more source

'The role of ferroptosis in Niemann-Pick disease'

openLa malattia di Niemann-Pick di tipo C (NPCD) è una malattia genetica rara appartenente al gruppo di malattie da accumulo lisosomiale. Questa patologia è principalmente causata dalla mutazione del gene npc1 che codifica per una proteina della ...
MAIORINO, SOFIA
core  

[Niemann-Pick disease (type C)].

Srpski arhiv za celokupno lekarstvo, 2006
A 15-year old girl with slowly progressive gait and speech disorders, and with impairment of mental ability, is decsribed. The disease appeared 18 months before the first hospitalization at the Department of Neurology and Physchiatry for Children and Young People.
D D, Milovanovitsh, A, Janeva, V, Jovanovitsh   +2 more
openaire   +1 more source

Pfrieger's Digest Niemann-Pick Type C Disease Issue 6; September 2021 - April 2022

, 2022
Summaries of latest research advances related to Niemann-Pick type C disease based on selected peer-reviewed publications in scientific journals. Revised version.Summaries of latest research advances related to Niemann-Pick type C disease based on ...
Pfrieger, Frank W
core  

The Pick Knitwear Story: 1856-1956

, 1956
An account of ]. PICK & SONS LTD LEICESTER Manufacturers for a hundred years.
Pick, J. B.
core  

The experience of living with Niemann-Pick type C: a patient and caregiver perspective. [PDF]

Orphanet J Rare Dis, 2023
Golden E, van Gool R, Cay M, Goodlett B, Cao A, Al-Hertani W, Upadhyay J.   +6 more
europepmc   +1 more source

The Pick Knitwear Story, Book Two: 1956-1991

, 1991
An account of ]. PICK & SONS LTD LEICESTER Manufacturers for a hundred years.
Pick, J. B.
core  

Impaired insulin signaling in an animal model of Niemann-Pick type C disease

, 2012
Impaired insulin signaling in an animal model of Niemann-Pick type C ...
B S Wong (13699093), M L Lim (13728946), Steve Cheung (13063932), C C Chua (13606417), Q R Ong (13729075)   +4 more
core  

Glycosphingolipids are linked to elevated neurotransmission and neurodegeneration in a Drosophila model of Niemann Pick type C. [PDF]

Dis Model Mech, 2023
Eberwein AE, Kulkarni SS, Rushton E, Broadie K.   +3 more
europepmc   +1 more source

Psychiatric burden in a cohort of adults with Niemann Pick type C disease: from psychotic symptoms to frontal lobe behavioral disorders. [PDF]

Orphanet J Rare Dis, 2023
Morin A, Carle G, Ponchel A, Fernández-Eulate G, Nadjar Y.   +4 more
europepmc   +1 more source