Results 71 to 80 of about 24,478,248 (209)

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

Experimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari, Helia Mardani, Mohammad Amin Karimi, MohammadHossein Sahami Gilan, Helia Hemmat, Fatemeh Shoja, Nooshin Enayati Soofi, Ghazaleh Eslamian   +7 more
wiley   +1 more source

Hypoplasia of the corpus callosum in Niemann-Pick type C disease

, 1994
In two unrelated patients with Niemann-Pick type C disease MRI showed symmetrical cerebral and cerebellar atrophy and hypoplasia of the corpus callosum.
FEDERICO, A., PALMERI, S., BATTISTI, C., GUAZZI, G. C.   +3 more
core   +1 more source

Norm Circles and the Limitations of European Union Normative Projection in Afghanistan

Journal for the Theory of Social Behaviour, Volume 56, Issue 4, December 2026.
ABSTRACT Norm diffusion research explains the international travel of norms in semantic terms, through resonance, framing, grafting and localisation. Such accounts presuppose norms to be portable objects whose identity persists through transit. Yet, ontologically, norms exert causal force only where a real social group endorses and enforces them.
Oz Hassan
wiley   +1 more source

Trial of N-Acetyl-l-Leucine in Niemann-Pick Disease Type C. [PDF]

BACKGROUND Niemann-Pick disease type C is a rare lysosomal storage disorder. We evaluated the safety and efficacy of N-acetyl-l-leucine (NALL), an agent that potentially ameliorates lysosomal and metabolic dysfunction, for the treatment of Niemann ...
Jones, Simon, Kay, Richard, Hahn, Andreas, Marquardt, Thorsten, Wibawa, Pierre, Sivananthan, Siyamini, Kolnikova, Miriam, Schneider, Susanne A, Gowing, Francesca, Mengel, Eugen, Martakis, Kyriakos, Walterfang, Mark, Arash-Kaps, Laila, Park, Julien H, Reichmannová, Stella, Ramaswami, Uma, Gissen, Paul, Strupp, Michael, Gautschi, Matthias, Bremova-Ertl, Tatiana, Brands, Marion, Foltan, Tomas   +21 more
core   +1 more source

Golgi localization and phosphorylation of oxysterol binding protein in Niemann-Pick C and U18666A-treated cells

Journal of Lipid Research, 2001
Oxysterol binding protein (OSBP) translocation between Golgi and vesicular/cytoplasmic compartments is affected by conditions that alter cholesterol and sphingomyelin homeostasis, indicating a role in lipid and sterol regulation in this organelle.
Abbas Mohammadi, Ryan J. Perry, Margo K. Storey, Harold W. Cook, David M. Byers, Neale D. Ridgway   +5 more
doaj   +1 more source

Progressive Cognitive Decline and Pyramidal Signs in a Patient With a Novel Homozygous c.395A>T; p.Lys132Met Mutation in CHCHD2

Clinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT Biallelic CHCHD2 variants are rare. We report a consanguineous man with a novel homozygous CHCHD2 c.395A>T (p.Lys132Met) variant who developed progressive cognitive decline, apraxia, oculomotor impairment, and pyramidal signs without parkinsonism.
Mehri Salari, Arash Soltani, Masoud Etemadifar, Kamran Rezaei   +3 more
wiley   +1 more source

Malaria mosquito antimicrobial defence requires immunity and detoxification gene regulation by Lola

Insect Molecular Biology, Volume 35, Issue 5, Page 576-593, October 2026.
Malaria mosquito antimicrobial defence requires upregulation of lola. Attenuation of lola in the midgut of Anopheles albimanus mosquitoes inhibits the upregulation of immunity genes induced by challenge. Putative target genes of the Lola transcription factor were revealed by lola attenuation, including Cecropin‐C, Draper, PPAF2, Clip‐domain serine ...
Heidi Espadas‐Álvarez, Verónica Valverde‐Garduño   +1 more
wiley   +1 more source

An Unusual Presentation of Copper Metabolism Disorder and a Possible Connection With Niemann-Pick Type C

, 2011
Abnormal copper metabolism has been linked with neurological disorders, such as Wilson and Menkes disease. Another disorder causing symptoms similar to copper metabolism disorder is Niemann-Pick type C.
Marc C. Patterson, Edward S. Johnson, Helly R. Goez, Francois D. Jacob, Jerome Y. Yager, Robert D. Fealey, Vijay Ramaswamy, Rabin Persad   +7 more
core   +1 more source

Type C Niemann-Pick disease [PDF]

British Journal of Haematology, 2000
Kennedy, G A, Cobcroft, R, Marlton, P, Silburn, P, Walsh, M, Boyle, R   +5 more
openaire   +4 more sources

Cognitive impairment profile in adult patients with Niemann pick type C disease

Orphanet Journal of Rare Diseases, 2017
Background Cognitive impairment is one of the core symptoms of Niemann Pick type C (NPC) disease, but few data concerning the neuropsychological profile of NPC patients are available.
Camille Heitz, Stéphane Epelbaum, Yann Nadjar   +2 more
doaj   +1 more source