Results 51 to 60 of about 116,586 (170)

Integrated In Silico Discovery of Thymoquinone Analogs Targeting the Keap1–Nrf2 Pathway for Amyotrophic Lateral Sclerosis Therapy

ChemistryOpen, Volume 15, Issue 9, September 2026.
Integrated in silico discovery of thymoquinone analogs as potent Keap1 inhibitors for ALS therapy. Using validated QSAR, docking, and 200 ns MD simulations, we identified brain‐penetrant leads (CHEMBL3416163, CHEMBL4636830, and CHEMBL221598) with binding affinities up to fourfold stronger than thymoquinone, offering a targeted strategy to restore redox
Jabir C. Nalicho, Petro E. Mabeyo, Andrew S. Paluch, Lucas Paul   +3 more
wiley   +1 more source

ANTIHYPERTENSIVE EFFECTS OF NIGELLA SATIVA: WEIGHING THE EVIDENCE [PDF]

, 2019
Objective: Hypertension causes 7.5 million deaths annually worldwide. Antihypertensive drugs cause side effects, potentially leading to non-adherence, hence uncontrolled hypertension and increased risk of cardiovascular morbidity and mortality. Therefore,
LOKESWARA, ANGGA WIRATAMA, PRIHASTAMA, RAFINDHRA ADHITYA, AFARATU, KEVIN, FARIDA, SITI   +3 more
core   +1 more source

Efektivitas ekstrak biji jintan hitam (Nigella sativa) dalam menghambat pertumbuhan mikroorganisme rongga mulut pada cetakan polyvinyl siloxane

, 2012
Background. Impression materials can be one of the oral cavity microorganisms transmission media. To prevent this, polyvinyl siloxane impression needs to be disinfected. Purpose.
Amalia, Fitri Rizki, Rostiny, Kamadjaja, Josef   +2 more
core   +1 more source

Medicinal Plants in Poultry During Post‐Antibiotic Era in One‐Health Approach: An Extensive Review

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
One‐Health is a gift of 21st century and human being must fulfill his obligations. Poultry industry is growing steadily and faster than other food animals' industries, and intensive poultry production is the frontier in producing antibiotic‐free foods for human beings.
Alireza Talebi, Arman Savari
wiley   +1 more source

hymoquinone: The Bioactive Component of Nigella Sativa [PDF]

, 2013
Nigella Sativa (NSJ/dan izole edilen timokinon (TQ) özellikle antioksidan, antihiperlipidemik, antidiyabetik, antiinflamatuar, gastroprotektif, hepatoprotektif gibi pek çok yararlı etkilere sahiptir.
Bacak Güllü, Elif, Avcı, Gülcan
core   +1 more source

Nanotechnology‐Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano‐immunostimulants improve fish health through targeted and controlled delivery of immunostimulatory compounds. Biodegradable polymeric and lipid‐based nanocarriers enhance immune responses, bioavailability and disease resistance while reducing antibiotic dependence and environmental impact.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Биологически активные вещества перспективных видов Nigella L. и их изменения при обработке электромагнитным излучением

Фактори експериментальної еволюції організмів, 2016
Aim. The evaluation of biologically active compounds of seeds of three Nigella species cultivated in Belarus and their changes under the influence of electromagnetic radiation. Methods.
С. Н. Шиш, Е. Д. Скаковский, Л. Ю. Тычинская, А. Г. Шутова, Е. В. Спиридович   +4 more
doaj  

Dietary Terpenoids in Advancing Biofilm‐Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano‐Facilitated Functional Delivery

Cell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder, Aditi Dey, Debasmita Bhattacharya, Dibyajit Lahiri, Moupriya Nag, Sudhriti Maity, Navin Kumar, Soumya Pandit, Vaseem Raja, Shubham Sharma, Shashi Prakash Dwivedi, Mithul Rajeev, Juwita Ratna Dewi, Lola Sanayeva, Dilbar Azimova   +14 more
wiley   +1 more source

Effect of ethanol extract of nigella sativa L seeds and propofol on BDNF protein level as neuroplasticity and neuroprotection of traumatic brain injury in rats [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research
Background Traumatic brain injury (TBI) is a change in brain function or evidence of brain pathology caused by external mechanical forces. Brain Derived Neurotrophic Factor (BDNF) is a neurotropin that functions as a neuron protective.
Kulsum Kulsum, Syahrul Syahrul, Kartini Hasbalah, Ummu Balqis   +3 more
doaj   +1 more source

Comparative Study in Seed Yield and Flowers Attractivity to Bee Visitors Between Nigella Sativa L. and Nigella Damascena L. (Ranunculaceae) Grown Under Semiarid Conditions

Italian Journal of Agronomy, 2008
This experiment was carried out during the growing season 2005 at the campus of Jordan University of Science and Technology (32°22” N, 35°49” E), Jordan.
Ahmad Alqudah, Nezar Samarah, Abd Al-Majeed Al-Ghzawi, Shahera Zaitoun   +3 more
doaj   +1 more source