A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu +10 more
wiley +1 more source
High-Temperature Oxidation Resistance of Fe-Free AlCoCrNiNb<sub>0.2</sub> and AlCoCr<sub>0.5</sub>NiNb<sub>0.2</sub> High-Entropy Alloys. [PDF]
Samoilova O +4 more
europepmc +1 more source
RvD5 effectively alleviates UC by inhibiting STAT1 signaling to reduce CXCL8 expression in colonic epithelial cells via activation of GPR101, which subsequently decreases the infiltration of neutrophils in the colonic mucosal epithelium. Epimedin A1, a natural allosteric inhibitor of 5‐LOX, demonstrates potential as a therapeutic agent for UC by ...
Pengxiang Guo +9 more
wiley +1 more source
Elastic Anisotropy in BCC Ti-X Alloys (X = V, Nb, Ta) Determined from First Principles. [PDF]
Sobczak C +4 more
europepmc +1 more source
Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu +4 more
wiley +1 more source
Sideband injection locking of microwave frequency combs in a superconducting optomechanical circuit. [PDF]
Jeong J, Ryu Y, Jung H, Cha J.
europepmc +1 more source
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Alkaline Earth Metal Fluorides (MgF<sub>2</sub>, CaF<sub>2</sub>, SrF<sub>2</sub>, BaF<sub>2</sub>) and Nb<sub>2</sub>O<sub>5</sub> Effect on the Structural and Optical Properties of New Fluorophosphoniobate Glasses. [PDF]
Olivetti Estevam da Silva L +4 more
europepmc +1 more source
Thermal transport in smooth‐interface superlattices is studied using the phonon Wigner transport equation, which captures both particle‐like and wave‐like contributions. A minimum in cross‐plane thermal conductivity emerges with increasing period thickness, signaling a crossover from coherent to incoherent phonon transport.
Jin Yang +3 more
wiley +1 more source
Dual-band electrochromism in two-dimensional layered TT-Nb<sub>2</sub>O<sub>5</sub>. [PDF]
Zhang W, Milliron DJ.
europepmc +1 more source

