Results 221 to 230 of about 27,228 (306)

Hybrid modeling for optimizing cell cultivation in mAb production using a small‐scale automated experimental platform

open access: yesAIChE Journal, EarlyView.
Abstract This work presents the optimization of cell cultivation for monoclonal antibody (mAb) production. We developed a hybrid model describing the effects of multiple process variables on antibody productivity and impurity generation. An automated platform with 12 × 250 mL bioreactors was set up.
Kosuke Nemoto   +6 more
wiley   +1 more source

Scale‐up of Streptomyces species cultivations based on the morphological response to the energy dissipation rate

open access: yesAIChE Journal, EarlyView.
Abstract Filamentous microorganisms exhibit complex morphologies that influence product formation and are affected by various bioprocess parameters. Consistent morphology is therefore essential for comparable results during scale‐up. This study investigates the scale‐up of Streptomyces species (Streptomyces spp.) cultivations from shake flasks to ...
Gesa Brauneck   +12 more
wiley   +1 more source

Noradrenergic modulation of pheromone-induced odor learning and brain activation in newborn rabbits. [PDF]

open access: yesSci Rep
Ducourneau EG   +6 more
europepmc   +1 more source

Evolution of Physical Intelligence Across Scales

open access: yesAdvanced Intelligent Discovery, EarlyView.
By following the evolution of physical intelligence across scales, this article shows how intelligence arises from materials, structures, physical interactions, and collectives. It establishes physical intelligence as the evolutionary foundation upon which embodied intelligence is built.
Ke Liu   +7 more
wiley   +1 more source

Infant pigs demonstrate motor adaptation across multiple physiologic functions during feeding in response to dynamic changes in milk flow rate. [PDF]

open access: yesJ Appl Physiol (1985)
Kennedy ME   +9 more
europepmc   +1 more source

A Case of Malignant Melanoma of the Nipple

open access: bronze, 2014
Yayoi Adachi   +3 more
openalex   +2 more sources

Severe Occupational Hypersensitivity Pneumonitis: A Case Series of Four Patients Requiring Lung Transplantation

open access: yesAmerican Journal of Industrial Medicine, EarlyView.
ABSTRACT Hypersensitivity pneumonitis (HP) is an immune‐mediated interstitial lung disease triggered by repeated inhalation of organic or chemical antigens. Occupational exposures account for approximately 19% of all cases. Early diagnosis, identification of the responsible antigen(s), and immediate avoidance of exposure are crucial to prevent ...
Ludwig Frei‐Stuber   +6 more
wiley   +1 more source

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