Results 301 to 310 of about 76,730 (376)

The Missing Link: Connecting Cultivation Conditions and Refolding Performance via Inclusion Body Biophysical Properties

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion bodies (IBs) frequently form during the expression of heterologous proteins in Escherichia coli and are therefore important in pharmaceutical production. While it is accepted that cultivation conditions affect cultivation performance, the link to refolding performance remains unexplored. This study proposes that this interplay relies,
Matthias Rüdt, Aymerick Bussien, Joan Cortada‐Garcia, Holger Morschett, Hauke Holm, Chiara Mazzucchelli, Karlheinz Flicker   +6 more
wiley   +1 more source

Pagetoid squamous cell carcinoma in situ (Pagetoid bowen's disease) of the nipple in an older male patient: a case report and literature review. [PDF]

BMC Geriatr
Chen X, An L, Zhao Y, Jia Y.
europepmc   +1 more source

Low Oxygen Availability Increases Itaconate Production by Ustilago maydis

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Itaconic acid is a monomer for high performance polymers. While produced in industry with the filamentous fungi Aspergillus terreus, the production with the smut fungus Ustilago maydis was proposed recently. The strict aerobic process suffers from high power input via gassing and stirring. Here, we investigated in detail possible scenarios for
Marianne Volkmar, Wolfgang Laudensack, Felix Bartzack, Niklas Erdmann, Sonja Schönrock, Emely Fuderer, Dirk Holtmann, Lars M. Blank, Roland Ulber   +8 more
wiley   +1 more source

Implant-based Cryopreserved Autologous Free Nipple Grafting for Breast Reconstruction: The ICEBERG Technique. [PDF]

Plast Reconstr Surg Glob Open
Patel SS, Lu NE, Xia T, Mailey BA.
europepmc   +1 more source

AutoML‐Driven Soft Sensors for Real‐Time Monitoring of Amino Acids in Mammalian Perfusion Cultures

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Mammalian perfusion culture offers high productivity for complex biologics but presents operational challenges in maintaining process stability. Real‐time monitoring is essential to address such challenges while traditional analytical methods often fall short due to several limitations such as detection sensitivity and spectral overlap ...
Sun‐Jong Kim, Minouk Lee, Daehwan Kim, Seongkyu Yoon, Dong‐Yup Lee   +4 more
wiley   +1 more source

Are Artificial Intelligence and Circular Economy Activities ‘Run‐of‐the‐Mill’ in Integrated Reporting?

Business Strategy and the Environment, EarlyView.
ABSTRACT This study aims to investigate the nexus of artificial intelligence (AI) and circular economy (CE) activities in integrated reporting (IR) practices. The study used data on the top 100 most sustainable corporations provided by Corporate Knights, which analyses roughly 7000 public firms with annual revenue of at least US$ $1 billion and the Dow
Sarfraz Nazir, Federica Doni, Alessandro Capocchi, Amna Sarfraz   +3 more
wiley   +1 more source

A Unique Acquired Athletic Dermatologic Condition in a Half Marathon Participant: An Autobiographical Case Report of Sports-Associated Clothing Related Axillary Tangled Clumped Hairs (SCRATCH). [PDF]

Cureus
Cohen PR.
europepmc   +1 more source

Iterative hybrid model based optimization of rAAV production

Biotechnology Progress, EarlyView.
Abstract Changes in serotype or genetic payload of recombinant adeno associated virus (rAAVs) gene therapies require adapting the transfection conditions of the upstream HEK293 cultivations. This study adopts an iterative model‐based experiment design approach, where increasing data availability is leveraged to evolve models of different complexity ...
Claudio Müller, Gerald Siegwart, Susanne Heider, Michael Sokolov, Angela Botros, Alexandra Umprecht, Moritz von Stosch, Mariano Nicolas Cruz Bournazou   +7 more
wiley   +1 more source

Isolated congenital hair tuft at an unusual location. [PDF]

JAAD Case Rep
Bhatty MA, Benedetto PX, Stultz T, Vidimos A.   +3 more
europepmc   +1 more source