Results 271 to 280 of about 51,034 (305)

NIR-II Fluorescence Imaging-Guided Photothermal Therapy with Amphiphilic Polypeptide Nanoparticles Encapsulating Organic NIR-II Dye

ACS Applied Bio Materials, 2020
NIR-II fluorescence imaging-guided photothermal therapy is a potential tumor therapeutic that has exhibited accurate diagnosis and noninvasive therapy of tumors. Here, we developed an organic macromolecular nanoparticle (PFD) by encapsulating a fluorophore with an amphiphilic polypeptide.
Quan Cheng, Tuanwei Li, Youliang Tian, Huiping Dang, Hongyun Qian, Changchang Teng, Kai Xie, Lifeng Yan   +7 more
openaire   +2 more sources

A simple POM clusters for in vivo NIR-II photoacoustic imaging-guided NIR-II photothermal therapy

Journal of Inorganic Biochemistry, 2020
Photoacoustic (PA) imaging in the second near-infrared (NIR-II) window exhibits enhanced deep-tissue imaging capability. Likely, cancer therapy in the NIR-II window could provide deeper penetration depth and higher exposure to laser over NIR-I. However, the traditional application of excitation light is still in the NIR-I window.
Yahong, Han, Botao, Qu, Juan, Li, Xiaomin, Zhang, Xiaoyang, Peng, Weihua, Li, Ruiping, Zhang   +6 more
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An Activatable Phototheranostic Nanoplatform for Tumor Specific NIR‐II Fluorescence Imaging and Synergistic NIR‐II Photothermal‐Chemodynamic Therapy

Small, 2023
AbstractThe phototheranostics in the second near‐infrared window (NIR‐II) have proven to be promising for the precise cancer theranostics. However, the non‐responsive and “always on” imaging mode lacks the selectivity, leading to the poor diagnosis specificity.
Yeneng Dai, Fan Zhang, Kai Chen, Zhiquan Sun, Zhihang Wang, Yuwen Xue, Meixing Li, Quli Fan, Qingming Shen, Qi Zhao   +9 more
openaire   +2 more sources

NIR-II fluorescence imaging guided tumor-specific NIR-II photothermal therapy enhanced by starvation mediated thermal sensitization strategy

Biomaterials, 2021
Photothermal therapy (PTT) is hampered by limited light penetration depth and cell thermoresistance induced by over-expressed heat shock proteins (HSPs). Herein, we proposed a tumor-specific enhanced NIR-II PTT through the starvation mediated thermal sensitization strategy.
Yeneng Dai, Zhiquan Sun, Honghai Zhao, Dashan Qi, Xiangyu Li, Diya Gao, Meixing Li, Quli Fan, Qingming Shen, Wei Huang   +9 more
openaire   +2 more sources

NIR-II Bioimaging

Fluorescent probes that emit in the second near-infrared region (NIR-II, 1000–1700 nm) possess unique advantages, including low photodamage and deep penetration into biological samples. Notably, NIR-II optical imaging can achieve tissue penetration as deep as 5–20 mm, which is critical for biomedical sensing and clinical applications.
P. Li, B. Tang
openaire   +1 more source

NIR-II upconversion nanomaterials for biomedical applications

Nanoscale
This review provides a comprehensive overview of recent biomedical applications of upconversion nanomaterials specifically within the near-infrared two-region (NIR-II) window (1000–1700 nm).
Ranran Luo, Chenxi Zhang, Zening Zhang, Pengchen Ren, Zhongsheng Xu, Yun Liu   +5 more
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A small-molecule dye for NIR-II imaging

Nature Materials, 2015
Fluorescent imaging of biological systems in the second near-infrared window (NIR-II) can probe tissue at centimetre depths and achieve micrometre-scale resolution at depths of millimetres. Unfortunately, all current NIR-II fluorophores are excreted slowly and are largely retained within the reticuloendothelial system, making clinical translation ...
Alexander L. Antaris, Hao Chen, Kai Cheng, Yao Sun, Guosong Hong, Chunrong Qu, Shuo Diao, Zixin Deng, Xianming Hu, Bo Zhang, Xiaodong Zhang, Omar K. Yaghi, Zita R. Alamparambil, Xuechuan Hong, Zhen Cheng, Hongjie Dai   +15 more
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NIR‐II AIEgens for Infectious Diseases Phototheranostics

Angewandte Chemie
AbstractPathogenic infectious diseases have persistently posed significant threats to public health. Phototheranostics, which combines the functions of diagnostic imaging and therapy, presents an extremely promising solution to block the spread of pathogens as well as the outbreak of epidemics owing to its merits of a wide‐spectrum of activity, high ...
Dingyuan Yan, Zheng Li, Michelle M. S. Lee, Ben Zhong Tang, Dong Wang   +4 more
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Atomic‐Precision Gold Clusters for NIR‐II Imaging

Advanced Materials, 2019
AbstractNear‐infrared II (NIR‐II) imaging at 1100–1700 nm shows great promise for medical diagnosis related to blood vessels because it possesses deep penetration and high resolution in biological tissue. Unfortunately, currently available NIR‐II fluorophores exhibit slow excretion and low brightness, which prevents their potential medical applications.
Haile Liu, Guosong Hong, Zhentao Luo, Junchi Chen, Junlei Chang, Ming Gong, Hua He, Jiang Yang, Xun Yuan, Lulin Li, Xiaoyu Mu, Junying Wang, Wenbo Mi, Jian Luo, Jianping Xie, Xiao‐Dong Zhang   +15 more
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Aggregation‐Induced Emission Near‐Infrared (NIR)‐II‐Conjugated Polymers Coupled With Nonconjugated Segments for NIR‐II Fluorescence Imaging–Guided NIR‐II Photothermal Therapy

Macromolecular Chemistry and Physics
AbstractThe development of conjugated polymer–based water‐soluble nanoparticles for near‐infrared‐II (NIR‐II) fluorescence (FL; 1000–1700 nm)‐guided photothermal therapy holds promise in advancing cancer treatment. However, excessive nonradiative decay leads to almost complete quenching of conjugated polymers’ fluorescence.
Zixin Hu, Jiarong He, Chenhang Xi, Sicheng Xu, Qingming Shen, Pengfei Chen, Pengfei Sun, Quli Fan   +7 more
openaire   +1 more source