Results 111 to 120 of about 937,811 (341)

Land Use Influence on the Characteristics of Groundwater Inputs to the Great Bay Estuary, New Hampshire [PDF]

, 2004
This research examines the sources and factors affecting nutrient-laden groundwater discharge to the Great Bay Estuary. To further understand this relationship, examination of groundwater residence time, a review of historic land uses, and nitrate source
Bacca-Cortes, Gabriel F., Ballestero, Thomas P., Roseen, Robert   +2 more
core   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Cultivo de cana-de-açúcar em argissolo tratado com lodo de esgoto: I - Disponibilidade de nitrogênio no solo e componentes de produção Sugarcane cultivation in a sewage-sludge treated ultisol: I - Soil nitrogen availability and plant yield

Revista Brasileira de Ciência do Solo, 2008
Adotando-se os devidos critérios agronômicos e sanitários, o lodo de esgoto pode ser utilizado como fonte de nutrientes, especialmente N, em solos agrícolas, revertendo em benefícios econômicos e ambientais.
Marcio Koiti Chiba, Maria Emília Mattiazzo, Fernando Carvalho Oliveira   +2 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Nitrate quantification: recent insights into enzyme-based methods

Reviews in Analytical Chemistry, 2016
Nitrate monitoring of environmental samples is essential to safeguard human and environmental health. Various non-enzymatic methods such as Griess reaction-based chemical method; Fourier transform infrared spectroscopy; chromatographic, electrochemical ...
Hooda Vinita, Sachdeva Veena, Chauhan Nidhi   +2 more
doaj   +1 more source

Glyphosate Bioremediation through the Sarcosine Oxidase Pathway Mediated by Lysinibacillus sphaericus in Soils Cultivated with Potatoes

Agriculture, 2019
Glyphosate-based herbicides (GBH) use has increased drastically over the last decade. This is true especially for potato crops due to their fast harvest cycle and high market demand.
Mario Pérez Rodríguez, Carol Melo, Elizabeth Jiménez, Jenny Dussán   +3 more
doaj   +1 more source

LXXX.—The nitration of aceto-m-toluidide [PDF]

, 1920
James Wilfred Cook, Oscar L. Brady
openalex   +1 more source

The effect of cattle slurry in combination with nitrate and the nitrification inhibitor dicyandiamide on in situ nitrous oxide and dinitrogen emissions [PDF]

, 2012
peer-reviewedA field study was conducted to determine the effect of the nitrification inhibitor dicyandiamide (DCD) on N2O and N2 emissions after cattle slurry (CS) application in the presence of nitrate (NO3) fertiliser on seven different occasions ...
Cahalan, E., Ernfors, M., Laughlin, Ronald J., McGeough, K. L., Muller, Christoph, Richards, Karl G., Watson, C. J.   +6 more
core   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source