Results 111 to 120 of about 642,149 (371)
The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley +1 more source
Global patterns of nitrate storage in the vadose zone
Global-scale nitrogen budgets developed to quantify anthropogenic impacts on the nitrogen cycle do not explicitly consider nitrate stored in the vadose zone.
M. Ascott+6 more
semanticscholar +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang+11 more
wiley +1 more source
Water rotational jump driven large amplitude molecular motions of nitrate ions in aqueous potassium nitrate solution [PDF]
Molecular dynamics simulations of aqueous potassium nitrate solution reveal a highly complex rotational dynamics of nitrate ions where, superimposed on the expected continuous Brownian motion, are large amplitude angular jumps that are coupled to and at least partly driven by similar large amplitude jump motions in water molecules which are associated ...
arxiv
Overexpression of a pH-sensitive nitrate transporter in rice increases crop yields
Significance Significant progress has been made in our understanding of plant adaptive responses to maintain cellular pH under varied N supply forms. Rice is a plant adapted to grow in waterlogged or dryland environments, in contrast to other crops, such
Xiaorong Fan+9 more
semanticscholar +1 more source
Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo+2 more
wiley +1 more source
Properties of Confined Ammonium Nitrate Ionic Liquids [PDF]
Ethylammonium nitrate (EAN) and propylammonium nitrate ionic liquids confined between polar glass plates and exposed to a strong magnetic field demonstrate gradually slowing diffusivity, a process that can be reversed by removing the sample from the magnetic field.
arxiv
Electrocatalytic Nitrate Reduction for Sustainable Ammonia Production
Phebe H. van Langevelde+2 more
semanticscholar +1 more source
Nitrogen (N) availability is a major factor determining plant growth and productivity. Plants acquire inorganic N from the soil, mainly in the form of nitrate and ammonium.
Takushi Hachiya, H. Sakakibara
semanticscholar +1 more source
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source