Results 111 to 120 of about 642,149 (371)

Purification and characterization of a thermophilic NAD+‐dependent lactate dehydrogenase from Moorella thermoacetica

open access: yesFEBS Open Bio, EarlyView.
The thermophilic acetogenic model organism Moorella thermoacetica can utilize lactate as substrate. The formation of lactate by reduction of pyruvate is energetically favorable, but the reverse reaction, the oxidation of lactate to pyruvate with NAD+ as electron acceptor is challenging.
Florian P. Rosenbaum, Volker Müller
wiley   +1 more source

Global patterns of nitrate storage in the vadose zone

open access: yesNature Communications, 2017
Global-scale nitrogen budgets developed to quantify anthropogenic impacts on the nitrogen cycle do not explicitly consider nitrate stored in the vadose zone.
M. Ascott   +6 more
semanticscholar   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Water rotational jump driven large amplitude molecular motions of nitrate ions in aqueous potassium nitrate solution [PDF]

open access: yesarXiv, 2016
Molecular dynamics simulations of aqueous potassium nitrate solution reveal a highly complex rotational dynamics of nitrate ions where, superimposed on the expected continuous Brownian motion, are large amplitude angular jumps that are coupled to and at least partly driven by similar large amplitude jump motions in water molecules which are associated ...
arxiv  

Overexpression of a pH-sensitive nitrate transporter in rice increases crop yields

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
Significance Significant progress has been made in our understanding of plant adaptive responses to maintain cellular pH under varied N supply forms. Rice is a plant adapted to grow in waterlogged or dryland environments, in contrast to other crops, such
Xiaorong Fan   +9 more
semanticscholar   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

open access: yesFEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo   +2 more
wiley   +1 more source

Properties of Confined Ammonium Nitrate Ionic Liquids [PDF]

open access: yesarXiv, 2018
Ethylammonium nitrate (EAN) and propylammonium nitrate ionic liquids confined between polar glass plates and exposed to a strong magnetic field demonstrate gradually slowing diffusivity, a process that can be reversed by removing the sample from the magnetic field.
arxiv  

Electrocatalytic Nitrate Reduction for Sustainable Ammonia Production

open access: yesJoule, 2021
Phebe H. van Langevelde   +2 more
semanticscholar   +1 more source

Interactions between nitrate and ammonium in their uptake, allocation, assimilation, and signaling in plants.

open access: yesJournal of Experimental Botany, 2016
Nitrogen (N) availability is a major factor determining plant growth and productivity. Plants acquire inorganic N from the soil, mainly in the form of nitrate and ammonium.
Takushi Hachiya, H. Sakakibara
semanticscholar   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

open access: yesFEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy   +14 more
wiley   +1 more source

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