Results 271 to 280 of about 963,417 (364)

Nitric oxide alterations following acute ductal constriction in the fetal lamb: a role for superoxide

, 2010
Jong‐Hau Hsu, Peter Oishi, Dean A. Wiseman, Yali Hou, Omar Chikovani, Sanjeev A. Datar, Enikö Sajti, Michael Johengen, Cynthia Harmon, Stephen M. Black, Jeffrey R. Fineman   +10 more
openalex   +2 more sources

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

Advanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu, Peng Wang, Qing‐Hua Shen, Qi‐Xin Guan, Zhi‐Yuan Li, Ying‐Ying Han, Xin‐Yi Zhang, Qing‐Yuan Hu, Cai‐Ping Tan   +8 more
wiley   +1 more source

Development of a human colorectal carcinoma cell-based platform for studying inducible nitric oxide synthase expression and nitric oxide signaling dynamics. [PDF]

Front Mol Biosci
Chen X, Grimm EA, Qin Y.
europepmc   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Phytoglobin Scavenging of Nitric Oxide Is Associated With Ethylene Reduction and Drought Tolerance in Oat (Avena sativa). [PDF]

Physiol Plant
Montilla-Bascon G, Cristescu SM, Mur LAJ, Prats E.   +3 more
europepmc   +1 more source

Unveiling the significance of inducible nitric oxide synthase: Its impact on cancer progression and clinical implications

Tong Chen
openalex   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

Advanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong, Chunyuan Zhao, Chengxi Li, Lin Weng, Zehan Ji, Peiqi Li, Jiqiang Lu, Danni Liu, Anni Yu, Tianyi Jiang, Shaokai Huang, Heng Liu, Xiao Chen, Zichun Hua   +13 more
wiley   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Nitric oxide-mediated modulation of reproductive resilience under cold stress in chickpea. [PDF]

Front Plant Sci
Kaur S, Padhiar D, Jha UC, Kumar S, Sharma KD, Parida SK, Siddique KHM, Prasad PVV, Nayyar H.   +8 more
europepmc   +1 more source

Investigation of the implications of nitric oxide on biofilm development

, 2008
Benjamin Ulfenborg
openalex   +1 more source