Fetal growth restriction is associated with placental metabolic adaptations. In small‐for‐gestational‐age placenta (SGA), cholesterol receptors and steroidogenic enzymes are upregulated, enhancing steroidogenesis. NAD salvage pathway is also increased to support NADP+/NADPH requirements.
Serena Xodo +4 more
wiley +1 more source
Evaluation of a 3,5-diethoxycarbonyl-1,4-dihydrocollidine diet-induced mouse model in a comparative experimental study of portal hypertension. [PDF]
Zhao JB +12 more
europepmc +1 more source
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka +3 more
wiley +1 more source
Glutamine enhances endothelial cell survival and vasodilation by increasing glutathione to reduce oxidative stress. [PDF]
Kheradmand M +8 more
europepmc +1 more source
ADAM17 and its proteolytic targets in disease pathogenesis
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley +1 more source
Probiotic and immune-modulatory capacities of three human gut-derived strains of Parabacteroides distasonis. [PDF]
Shamsuzzaman M, Dahal RH, Kim J.
europepmc +1 more source
Phagocytic hemocytes, independent of pericardial cells, modulate cellular immune responses on the dorsal vessel of mosquitoes, including the infection-induced reduction of the heart rate. [PDF]
Meier CJ +3 more
europepmc +1 more source
Citrulline-enhanced chicken resistance to <i>Salmonella Enteritidis</i> infection via urea cycle modulation and nitric oxide production. [PDF]
Jiang M +9 more
europepmc +1 more source
6-Nitrodopamine Release From Mouse Seminal Vesicles Is Dependent on Endothelial Nitric Oxide Synthase (eNOS) Activation. [PDF]
Britto-Júnior J +12 more
europepmc +1 more source

