Results 141 to 150 of about 63,869 (332)

Low‐Strain Flexible Ink‐Based Sensors Enable Hyperelastic Inflation Perception Via Geometric Patterning for Balloon‐Type Robots

open access: yesAdvanced Robotics Research, EarlyView.
Integrating proprioceptive capabilities in balloon‐type robots enhances safe human–machine interactions. Traditional pressure estimates are inadequate due to nonlinear relationships. Instead, embedding stretchable sensors effectively measures deformation. This design optimizes sensor geometry to minimize damage risks.
Wenchao Yue   +6 more
wiley   +1 more source

A Canine Musculoskeletal Robot for Investigating Biomechanical Functions During Locomotion

open access: yesAdvanced Robotics Research, EarlyView.
In this study, a dog limb musculoskeletal robot was developed using thin McKibben artificial muscles to investigate the effects of the dog's musculoskeletal structure on walking. Walking experiments were conducted in both indoor and outdoor environments, suggesting that the flexible structure of the dog's shoulders contributes to an increase in stroke ...
Hana Ito   +6 more
wiley   +1 more source

Inhibition of dimeric SARS-CoV-2 Mpro displays positive cooperativity and a mixture of covalent and non-covalent binding

open access: yesiScience
Summary: SARS-CoV-2 Mpro is a cysteine protease that acts as a symmetrical dimer and displays positive cooperativity for substrate turnover. A series of potent reversible covalent peptidomimetic aldehydes and nitriles was designed as Mpro inhibitors.
Krishna M. Padmanabha Das   +17 more
doaj   +1 more source

Analyzing the Catalytic Mechanism of the Fe-Type Nitrile Hydratase from \u3cem\u3eComamonas testosteroni\u3c/em\u3e Ni1 [PDF]

open access: yes, 2008
In order to gain insight into the catalytic mechanism of Fe-type nitrile hydratases (NHase), the pH and temperature dependence of the kinetic parameters kcat, Km, and kcat/Km along with the solvent isotope effect were examined for the Fe-type NHase from ...
Holz, Richard C., Rao, Saroja
core   +1 more source

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

open access: yesAdvanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer   +7 more
wiley   +1 more source

Designing High Performance Organic Donor Molecules for Photovoltaics

open access: yesAdvanced Theory and Simulations, EarlyView.
Systematically tuning the fusion pattern and length of the π$\pi$‐bridge, along with adjusting the electron‐withdrawing (EW) strength of the terminal groups in small‐molecule donor A-π-Core-π$\text{A-}\pi \text{-Core-}\pi$‐A architectures, enables predictable modulation of the system's opto‐electronic properties.
Fabian Bauch   +2 more
wiley   +1 more source

Disequilibrium Carbon, Oxygen, and Nitrogen Chemistry in the Atmospheres of HD 189733b and HD 209458b

open access: yes, 2011
We have developed 1-D photochemical and thermochemical kinetics and diffusion models for the transiting exoplanets HD 189733b and HD 209458b to study the effects of disequilibrium chemistry on the atmospheric composition of "hot Jupiters." Here we ...
A. J. Friedson   +121 more
core   +1 more source

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