Results 111 to 120 of about 255,274 (347)

Macrocyclic Molecular Glues for the 14‐3‐3/ChREBP Interaction: Affinity and Cooperativity in an Inverse Relationship

Angewandte Chemie, EarlyView.
Macrocycles are effective molecular glues to stabilize the 14‐3‐3/ChREBP interaction. Linker length modulation uncovered an inverse correlation between the macrocycle binding affinity to 14‐3‐3 and its cooperativity in 14‐3‐3/ChREBP stabilization.
Marloes A. M. Pennings, Merel A. W. van den Bosch, Ansgar Oberheide, Carlo J. A. Verhoef, Christian Ottmann, Albert J. Markvoort, Galen P. Miley, Luc Brunsveld   +7 more
wiley   +2 more sources

Metal-Free Supramolecular Reduction of Nitro Compounds into the Cucurbit[7]uril Cavity: Testing the Enabling Technique in Aqueous Media [PDF]

, 2023
Satenik Mkrtchyan, Vishal B. Purohit, Sehrish Sarfaraz, Muhammad Yar, Khurshid Ayub, Viktor O. Iaroshenko   +5 more
openalex   +1 more source

Characterization of di‐gital, tri‐gital, and tetra‐gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness

Animal Models and Experimental Medicine, EarlyView.
The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak, Lenka Tomasova, Marian Grman, Karol Ondrias   +3 more
wiley   +1 more source

Total Synthesis of (+)‐Melonine and (+)‐N4‐Oxy Melonine Enabled by an Intramolecular Alkene Diamination Reaction

Angewandte Chemie, EarlyView.
A complexity‐generating intramolecular alkene diamination constitutes the pivotal step in the enantioselective synthesis of the title natural products featuring a strained, cage‐like pentacyclic architecture. Abstract Among more than four thousand monoterpene indole alkaloids (MIAs) isolated to date, only a few feature a 2,2,3‐trisubstituted indoline ...
Vincent Goëlo, Qian Wang, Jieping Zhu
wiley   +2 more sources

Organic reaction in water. Part 31: diastereoselectivity in Michael additions of thiophenol to nitro olefins in aqueous media

Journal of the Brazilian Chemical Society, 2001
Thiophenol reacts with nitro olefins in aqueous media to give the corresponding nitro-sulfides in 58-95% yield. This procedure results in selective formation of the anti products.
Silva Flavia M. da, Jones Jr Joel
doaj  

(Z)-3-(9-Anthryl)-1-(4-chlorophenyl)-2-(4-nitro-1H-imidazol-1-yl)prop-2-en-1-one [PDF]

, 2009
Guang-Zhou Wang, Yi‐Hui Lu, Cheng‐He Zhou, Yiyi Zhang   +3 more
openalex   +1 more source

SYNTHESIS AND STUDY OF THE PHOTOCHROMIC BEHAVIOR OF SUBSTITUTED 6'-NITRO-1,3,3-TRIMETHYL-5-VINYLSPIRO(INDOLINO-2,2'-[2H]CHROMENES)

Тонкие химические технологии, 2013
Few 5-vinyl substituted 6’-nitro-1,3,3-trimethylspiro(indolino-2,2’-[2H]chromenes) (6’-nitro-spiropyrans) were synthesized by a one-step method from 5-formyl precursor – 5-formyl-6’-nitro-1,3,3-trimethylspiro(indolino-2,2’- [2H]chromene) (1).
A. V. Laptev, A. Yu. Lukin, N. V. Belikov, O. V. Demina, S. D. Varfolomeev, V. A. Barachevsky, A. A. Khodonov, V. I. Shvets   +7 more
doaj  

Heterocyclic Tricycles as Internal N-Glycosides from 2-Methyl-5-nitro-6-(2-nitrophenyl)-4-phenyl(2-furyl)tetrahydropyranols

Molecules, 2000
1-Methyl-10-nitro-11-phenyl(2-furyl)-2-aza-13-oxa-tricyclo[7.3.1.03,8]trideca-3,5,7-trienes 3 were synthesized via the reduction of the aromatic 2-nitro group of 2-methyl-5-nitro-6-(2-nitrophenyl)-4-phenyl(2-furyl)tetrahydropyranols 2 and subsequent ...
Klaus Peseke, Manfred Michalik, Lutz Götze, José Quincoces, Helmut Reinke   +4 more
doaj  

Ueberführung von o‐Nitro‐ und o, p‐Dinitro‐Benzylchlorid in Acridinderivate

, 1904
Carlo Baezner
openalex   +2 more sources

Pharmacological studies on sulfonamide derivatives (I). Toxicity of sulfamin, sulfathiazole and nitro- and amino-derivatives of diphenylsuljone

, 1952
Yao-Toiig CHANG
openalex   +2 more sources