Results 131 to 140 of about 173,810 (326)

Macrocyclic Molecular Glues for the 14‐3‐3/ChREBP Interaction: Affinity and Cooperativity in an Inverse Relationship

open access: yesAngewandte Chemie, EarlyView.
Macrocycles are effective molecular glues to stabilize the 14‐3‐3/ChREBP interaction. Linker length modulation uncovered an inverse correlation between the macrocycle binding affinity to 14‐3‐3 and its cooperativity in 14‐3‐3/ChREBP stabilization.
Marloes A. M. Pennings   +7 more
wiley   +2 more sources

Characterization of di‐gital, tri‐gital, and tetra‐gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak   +3 more
wiley   +1 more source

aci-nitro compounds

open access: yes, 2008
Citation: 'aci-nitro compounds' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.A00085 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

The 1-((diorganooxyphosphonyl)-methyl)-2,4- and -2,6-diamido benzenes [PDF]

open access: yes, 1989
1-((Diorgano oxyphosphonyl) methyl)-2,4- and -2,6-dinitro and diamino benzenes are prepared by nitrating an (organophosphonyl) methyl benzene to produce the dinitro compounds which are then reduced to the diamino compounds.
Kourtides, Demetrius A.   +1 more
core   +1 more source

Total Synthesis of (+)‐Melonine and (+)‐N4‐Oxy Melonine Enabled by an Intramolecular Alkene Diamination Reaction

open access: yesAngewandte Chemie, EarlyView.
A complexity‐generating intramolecular alkene diamination constitutes the pivotal step in the enantioselective synthesis of the title natural products featuring a strained, cage‐like pentacyclic architecture. Abstract Among more than four thousand monoterpene indole alkaloids (MIAs) isolated to date, only a few feature a 2,2,3‐trisubstituted indoline ...
Vincent Goëlo, Qian Wang, Jieping Zhu
wiley   +2 more sources

Synthesis of Nitro Compounds from Nitrogen Dioxide Captured in a Metal-Organic Framework. [PDF]

open access: yesJ Am Chem Soc, 2022
Li J   +10 more
europepmc   +1 more source

Aromatic cyclotriphosphazenes [PDF]

open access: yes, 1988
Four-Aminophenoxy cyclotriphosphazenes are reacted with maleic anhydride to produce maleamic acids which are converted to the maleimides. The maleimides are polymerized.
Fohlen, George M.   +2 more
core   +1 more source

A screening method for ranking chemicals by their fate and behaviour in the environment and potential toxic effects in humans following non-occupational exposure [PDF]

open access: yes, 2004
A large number of chemicals are released intentionally or unintentionally into the environment each year. These include thousands of substances that are currently listed worldwide and several hundred new substances added annually (Mücke et al., 1986 ...
Capelton, A   +2 more
core  

The Composition of Arylstibonic Acids [PDF]

open access: yes, 2010
This thesis describes a detailed ESI-MS investigation into the arylstibonic acids, organo-antimony-containing compounds that are currently of interest as anticancer reagents. Four arylstibonic acids, of nominal formula RC6H4SbO3H2 [R = p-chloro-, p-tolyl-
Wright, Cody Elvin
core   +1 more source

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