Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania. [PDF]
PLoS Pathogens, 2016 Drug discovery pipelines for the "neglected diseases" are now heavily populated with nitroheterocyclic compounds. Recently, the bicyclic nitro-compounds (R)-PA-824, DNDI-VL-2098 and delamanid have been identified as potential candidates for the treatment
Susan Wyllie +7 more
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Four pyrrole derivatives used as building blocks in the synthesis of minor-groove binders [PDF]
Acta Crystallographica Section E: Crystallographic Communications, 2017 The title nitropyrrole-based compounds, C7H8N2O4, (I) (ethyl 4-nitro-1H-pyrrole-2-carboxylate), its derivative C12H14N2O4, (II) [ethyl 4-nitro-1-(4-pentynyl)-1H-pyrrole-2-carboxylate], C15H26N4O3, (III) {N-[3-(dimethyamino)propyl]-1-isopentyl-4-nitro-1H ...
Alan R. Kennedy +3 more
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Sensitive Energetics from the N‐Amination of 4‐Nitro‐1,2,3‐Triazole
ChemistryOpen, 2020 Energetic N‐amino‐C‐nitro compounds 1‐amino‐4‐nitro‐1,2,3‐triazole and 2‐amino‐4‐nitro‐1,2,3‐triazole are characterized for the first time as energetic materials. These compounds were characterized chemically by nuclear magnetic resonance (NMR), Infrared
Dominique R. Wozniak +4 more
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Green Chemical Engineering, 2022 Development of the economic, environmentally friendly synthesis of amines from nitro compounds remains important and challenging. In this work, the graphene shell encapsulated none noble Ni-based catalysts were successfully designed and synthesized via ...
Jianguo Liu +3 more
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In pursuit of β-amino α-nitro β-trifluoromethyl ketones: nitro-Mannich vs Mannich-type reactions [PDF]
, 2017 The reactivity of alfa-nitro ketones with trifluoromethyl aldimines is studied for the first time. While under nitro-Mannich conditions only the facial stereoselectivity can be controlled, organocatalysed Mannich-type reactions allowed a complete control
Ballini +45 more
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The Major Heat Shock Proteins, Hsp70 and Hsp90, in 2-Methoxyestradiol-Mediated Osteosarcoma Cell Death Model [PDF]
, 2020 2-Methoxyestradiol is one of the natural 17β-estradiol derivatives and a potential novel anticancer agent currently being under evaluation in advanced phases of clinical trials.
Cappello F. +8 more
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2,6-Diiodo-4-nitrophenol, 2,6-diiodo-4-nitrophenyl acetate and 2,6-diiodo-4-nitroanisole: interplay of hydrogen bonds, iodo-nitro interactions and aromatic [pi]-[pi]-stacking interactions to give supramolecular structures in one, two and three dimensions [PDF]
, 2002 Peer reviewedPublisher ...
da Cunha, F R +5 more
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Evaluation of the effects of some benzimidazole derivatives on germination parameters of wheat varieties [PDF]
Journal of Agricultural Sciences (Belgrade)This study aims to investigate the effect of some benzimidazole derivatives on the germination parameters of bread and durum wheat varieties. These derivatives contain both unsubstituted and substituted benzimidazole structures to determine the effect of
Külen Seda, Dincer Sebla
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Application of nitroarene dioxygenases in the design of novel strains that degrade chloronitrobenzenes. [PDF]
, 2009 Widespread application of chloronitrobenzenes as feedstocks for the production of industrial chemicals and pharmaceuticals has resulted in extensive environmental contamination with these toxic compounds, where they pose significant risks to the health ...
Ju, Kou-San, Parales, Rebecca E
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Theory and Application of Dissociative Electron Capture in Molecular Identification [PDF]
, 2006 The coupling of an electron monochromator (EM) to a mass spectrometer (MS) has created a new analytical technique, EM-MS, for the investigation of electrophilic compounds.
Clougherty, Dennis P. +6 more
core +2 more sources