Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei [PDF]
OBJECTIVES: The objective of this study was to identify the mechanisms of resistance to nifurtimox and fexinidazole in African trypanosomes. METHODS: Bloodstream-form Trypanosoma brucei were selected for resistance to nifurtimox and fexinidazole by ...
Berriman, Matthew +5 more
core +3 more sources
Nitro-spojevi kao otapala, lijekovi, međuprodukti i eksplozivi [PDF]
This report is focused partly on the chemical development of some chemical functional groups, and partly on our own results connected with research by Vladimir Prelog in the last period of his work.
Mutak, S.
doaj
Heterogeneous reactions of particulate matter-bound PAHs and NPAHs with NO3/N2O5, OH radicals, and O3 under simulated long-range atmospheric transport conditions: reactivity and mutagenicity. [PDF]
The heterogeneous reactions of ambient particulate matter (PM)-bound polycyclic aromatic hydrocarbons (PAHs) and nitro-PAHs (NPAHs) with NO3/N2O5, OH radicals, and O3 were studied in a laboratory photochemical chamber. Ambient PM2.5 and PM10 samples were
Arey, Janet +8 more
core +2 more sources
Crystal structures of four indole derivatives as possible cannabinoid allosteric antagonists [PDF]
Acknowledgements We thank the EPSRC National Crystallography Service (University of Southampton) for the data collections and the EPSRC National Mass Spectrometry Service (University of Swansea) for the HRMS data.
Harrison, William T. A. +4 more
core +2 more sources
Novel solid-state emissive polymers and polymeric blends from a T-Shaped benzodifuran scaffold: A comparative study [PDF]
Two novel polyimines were synthesized from a benzodifuran based diamino monomer and two dialdehydes bearing bulky groups and a flexible spacer. The polymers display tuned luminescence performance according to the presence of half-salen groups. The effect
Caruso, U. +3 more
core +1 more source
Synthetic chemistry and biological activity of pentafluorosulphanyl (SF5) organic molecules [PDF]
Acknowledgements We thank the European Commission for financial support (Industry Academia Partnerships and Pathways project “PET BRAIN”, Contract No 251482). S.A.
Altomonte, Stefano, Zanda, Matteo
core +1 more source
ANALYSIS OF SOME FACTORS WHICH CONTRIBUTE TO NITRO INTOXICATION OF ANIMALS [PDF]
The accumulation of nitro compounds in plants depends on several factors, in particular: the doses and frequency of incorporation of organic and mineral fertilizers in the soil, the amount of nitro compounds accumulated in soil and plants, climatic ...
Larisa CREMENEAC, Valentina ABRAMOVA
doaj
Six novel benzimidazole derivatives, 5-nitro-2-phenyl -1-ethyl benzimidazol (5), 2- (p-bromophenyl)- 5-nitro- 1-ethyl benzimidazol (6), 2- (p-bromophenyl-5-nitro-1–cyclopentyl benzimidazol (7), 2- (p-bromophenyl) -5-nitro-1-cyclopentyl benzimidazol (8 ...
Abbas Ahmadi, Babak Nahri-Niknafs
doaj +1 more source
Performance of the ALOGPS 2.1 program for octanol-water partition coefficient prediction with organic chemicals on the Canadian Domestic Substances List [PDF]
The KOWWIN and ALOGPS octanol-water partition coefficient (K~ow~) estimation software programs were compared for their capacity to accurately predict log K~ow~ values of 1545 organic compounds on the publicly available Domestic Substances List (DSL) from
Kaya Forest, Sierra Rayne
core +2 more sources
A series of nine nitro group-containing chalcones were synthesized to investigate their anti-inflammatory and vasorelaxant activities via in vivo, ex vivo, and in silico studies.
Alam Yair Hidalgo +10 more
doaj +1 more source

