Results 231 to 240 of about 400,040 (309)

Chronic sleep deprivation promotes drug‐resistant epilepsy via the BMAL1‐mTOR‐P‐gp axis

Epilepsia Open, EarlyView.
Abstract Objective The interplay between chronic sleep deprivation and drug‐resistant epilepsy (DRE) has gained increasing attention. Brain and muscle Arnt‐like protein 1 (BMAL1), which is implicated in sleep disturbance, has an unclear role in DRE. We aimed to investigate the role of BMAL1 in sleep deprivation‐induced DRE. Methods A pentylenetetrazole
Xiaomeng Wang, Rui Li, Yuzhu Zhang, Yi Hu, Jingjiao Chen, Sijia Tian, Dong Zhou, Xiaosa Chi   +7 more
wiley   +1 more source

Genetically Engineered Nanobody–Recombinant Antibody Colloidal Gold Strip for Ultrasensitive Atrazine Detection in Fruits and Vegetables

Food Safety and Health, EarlyView.
A sensitive colloidal gold immunochromatographic assay for atrazine was successfully established using genetically engineered nanobody‐recombinant antibody, which overcame the shortcomings of traditional antigen‐antibody. ABSTRACT Colloidal gold immunochromatography (CG‐ICA) is distinguished by its cost‐effectiveness and rapid detection capabilities ...
Jiayong Bao, Peipei Li, A. M. Abd El‐Aty, Jing Zhao, Lingyuan Xu, Chenxi Guo, Jia Li, Xingmei Lei, Sensen Feng, Yi Liu, Si Chen, Fen Jin, Jing Wang, Lufei Zheng, Zhen Cao, Bruce D. Hammock, Maojun Jin   +16 more
wiley   +1 more source

Functionalized Quantum Dot-Based Portable Sensor for Dual Detection of Stress Biomarkers in Blood Serum and Saliva. [PDF]

J Biophotonics
Kishore A, Varughese AM, Roth B, Zeilinger C.   +3 more
europepmc   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, EarlyView.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

Numerical simulation of stability of diffusion depth of deterrents into cylindrical nitrocellulose composite under different conditions. [PDF]

BMC Chem
Al-Hetty HRAK, Al-Dulaimi AA, Saleem HM, Kianfar E.   +3 more
europepmc   +1 more source

Cigarette Smoke Exposure Attenuates T2R‐Mediated Apoptosis in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Tobacco use is associated with worse outcomes in head and neck squamous cell carcinoma (HNSCC). Bitter taste receptor (T2R) activation induces apoptosis via calcium‐dependent signaling, and higher T2R expression correlates with increased survival in HNSCC.
Kyle Polen, Sarah Sywanycz, Gavin Turner, Brianna L. Hill, Lily Huang, Zoey A. Miller, Casey Hanna, Lovely Raghav, Devraj Basu, Robert J. Lee, Ryan M. Carey   +10 more
wiley   +1 more source

Sensitive Visual Detection of Breast Cancer Cells via a Dual-Receptor (Aptamer/Antibody) Lateral Flow Biosensor. [PDF]

Biosensors (Basel)
Zhou Y, Wang J, Han Y, Ma M, Li J, Li H, Zhang X, Liu G.   +7 more
europepmc   +1 more source

S2Tag, a novel affinity tag for the capture and immobilization of coiled-coil proteins: Application to the study of human β-cardiac myosin. [PDF]

J Biol Chem
Barua B, Cail RC, Goldman YE, Ostap EM, Winkelmann DA.   +4 more
europepmc   +1 more source

The Growth Supporting Role of ZDHHC11 Is Linked to the MEF2B–BCL6 Regulatory Circuit in Burkitt Lymphoma

International Journal of Cancer, EarlyView.
MEF2B and BCL6 have established functions in germinal center B‐cell biology and lymphomagenesis. The mechanism of MEF2B deregulation and its significance for cell survival in Burkitt lymphoma however remain unclear. This study highlights MEF2B as a crucial transcription factor in Burkitt lymphoma and suggests ZDHHC11 as an upstream regulator of MEF2B ...
Lotteke J. Y. M. Ziel‐Swier, Karolina Rassek, Yichen Liu, Annika Seitz, Jasper Koerts, Debora de Jong, Bea Rutgers, Anastasiia Kompaniiets, Julia Przybył, Martine E. D. Chamuleau, Anke van den Berg, Agnieszka Dzikiewicz‐Krawczyk, Joost Kluiver   +12 more
wiley   +1 more source