Results 61 to 70 of about 35,042 (257)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Laser-written waveguide-integrated coherent spins in diamond

APL Photonics
Quantum emitters, such as the negatively charged nitrogen-vacancy center in diamond, are attractive for quantum technologies, such as nano-sensing, quantum information processing, and as a non-classical light source.
Yanzhao Guo, John P. Hadden, Federico Gorrini, Giulio Coccia, Vibhav Bharadwaj, Vinaya Kumar Kavatamane, Mohammad Sahnawaz Alam, Roberta Ramponi, Paul E. Barclay, Andrea Chiappini, Maurizio Ferrari, Alexander Kubanek, Angelo Bifone, Shane M. Eaton, Anthony J. Bennett   +14 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Vibrationally resolved optical excitations of the nitrogen-vacancy center in diamond

npj Computational Materials, 2022
A comprehensive description of the optical cycle of spin defects in solids requires the understanding of the electronic and atomistic structure of states with different spin multiplicity, including singlet states which are particularly challenging from a
Yu Jin, Marco Govoni, Giulia Galli
doaj   +1 more source

Enhancement of the Zero Phonon Line emission from a Single NV-Center in a Nanodiamond via Coupling to a Photonic Crystal Cavity

, 2010
Using a nanomanipulation technique a nanodiamond with a single nitrogen vacancy center is placed directly on the surface of a gallium phosphide photonic crystal cavity. A Purcell-enhancement of the fluorescence emission at the zero phonon line (ZPL) by a
Barth, Michael, Benson, Oliver, Döscher, Henning, Hannappel, Thomas, Kewes, Güter, Nüsse, Nils, Schell, Andreas W., Schoengen, Max, Wolters, Janik, öhel, Bernd L   +9 more
core   +1 more source

Controllable Non-Markovianity for a Spin Qubit in Diamond [PDF]

, 2018
We present a flexible scheme to realize non-artificial non-Markovian dynamics of an electronic spin qubit, using a nitrogen-vacancy center in diamond where the inherent nitrogen spin serves as a regulator of the dynamics.
Haase, Jan F., Huelga, Susana F., Jelezko, Fedor, Naydenov, Boris, Plenio, Martin B., Rosskopf, Joachim, Smirne, Andrea, Stacey, Alastair, Unden, Thomas, Vetter, Philipp J.   +9 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

High-Dynamic-Range Integrated NV Magnetometers

Micromachines
High-dynamic-range integrated magnetometers demonstrate extensive potential applications in fields involving complex and changing magnetic fields. Among them, Diamond Nitrogen Vacancy Color Core Magnetometer has outstanding performance in wide-range and ...
Tianning Wang, Zhenhua Liu, Yankang Liu, Bo Wang, Yuanyuan Shen, Li Qin   +5 more
doaj   +1 more source

Eddy-Current Imaging with Nitrogen-Vacancy Centers in Diamond [PDF]

Physical Review Applied, 2019
We demonstrate microwave-free eddy-current imaging using nitrogen-vacancy centers in diamond. By detecting the eddy-current induced magnetic field of conductive samples, we can distinguish between different materials and shapes and identify structural defects.
Chatzidrosos, Georgios, Wickenbrock, Arne, Bougas, Lykourgos, Zheng, Huijie, Tretiak, Oleg, Yang, Yu, Budker, Dmitry   +6 more
openaire   +2 more sources

Adjustment of Coatings Morphology and Particle Distribution of Layered Silicates by Freeze‐Drying for Improved Gas Barriers

Advanced Engineering Materials, EarlyView.
Freeze‐drying of layered silicate is the key to get coatings with superior gas barrier. Freeze‐drying of layered silicates modified with dodecylamine (DDA) is a highly effective technique for the preparation of barrier pigments that significantly mitigate the permeation of oxygen, water vapor, and hydrogen through polymer films containing these ...
Joshua Lommes, Moritz Bätcher, Andrea Deißenberger, Volkmar Stenzel, Andreas Hartwig   +4 more
wiley   +1 more source