Results 81 to 90 of about 3,450,809 (399)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Critical loads for nutrient nitrogen for soil-vegetation systems [PDF]

open access: yes, 1995
Members of the UK Critical Loads Advisory Group (CLAG) have calculated critical loads for nutrient nitrogen to produce maps for Great Britain. The results of three methods, based upon the conclusions from the Lokeberg workshop are described below. Two of
Brown, M.   +3 more
core  

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Nitrogen gross balance in farms specialised in plant production in selected regions of Poland

open access: yesAgronomy Science, 2011
The aim of the performed investigations was to evaluate nitrogen management in farms specialising in plant production situated in the following voivodeships: Wielkopolskie, Dolnośląskie, Opolskie and Mazowieckie.
JERZY KUPIEC   +3 more
doaj  

Fungicide Protection as an Agrotechnical Treatment Reducing Nitrogen Gap in Winter Wheat—A Case Study

open access: yesAgronomy
Protection of high-yielding winter wheat (WW) with fungicides increases the productivity of nitrogen (N) present in the soil–crop system during the growing season. As a consequence of the action of fungicides, the nitrogen gap (NG) reduces.
Agnieszka Andrzejewska   +2 more
doaj   +1 more source

Nutritional Practice and Nitrogen Balance in Elite Japanese Swimmers during a Training Camp

open access: yesSports, 2021
The protein requirement in athletes increases as a result of exercise-induced changes in protein metabolism. In addition, the frequency, quantity, and quality (i.e., leucine content) of the protein intake modulates the protein metabolism.
Ami Mizugaki   +4 more
doaj   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

open access: yesMolecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp   +13 more
wiley   +1 more source

In Vitro Crude Protein Digestibility of Insects: A Review

open access: yesInsects, 2022
The high protein content of insects has been widely studied. They can be a good food alternative, and therefore it is important to study the effect of digestion on their protein.
María Rodríguez-Rodríguez   +3 more
doaj   +1 more source

Mineral nitrogen sources differently affect root glutamine synthetase isoforms and amino acid balance among organs in maize

open access: yesBMC Plant Biology, 2015
BackgroundGlutamine synthetase (GS) catalyzes the first step of nitrogen assimilation in plant cell. The main GS are classified as cytosolic GS1 and plastidial GS2, of which the functionality is variable according to the nitrogen sources, organs and ...
B. Prinsi, L. Espen
semanticscholar   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

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